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胃癌的流行病学——变化趋势与全球差异

Epidemiology of Gastric Cancer-Changing Trends and Global Disparities.

作者信息

Inoue Manami

机构信息

National Cancer Center Institute for Cancer Control, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

出版信息

Cancers (Basel). 2024 Aug 24;16(17):2948. doi: 10.3390/cancers16172948.

DOI:10.3390/cancers16172948
PMID:39272806
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11394435/
Abstract

Overall, the past century has seen a substantial decline in gastric cancer, attributable to decreases in risk factors such as infection, tobacco smoking, and the intake of salt-preserved food. One potential preventive strategy for those at high risk is eradication for infected subjects, but confirmation of this effect awaits longer follow-up. Obesity continues to advance and may cause increases in cardia cancer, particularly in Western populations, and careful monitoring of this outcome is warranted in both Western and Asian populations. These changes in gastric cancer epidemiology foreshadow a new era in gastric cancer control and warrant further monitoring of descriptive patterns and risk factors.

摘要

总体而言，在过去的一个世纪里，胃癌发病率大幅下降，这归因于感染、吸烟和腌制食品摄入等风险因素的减少。对于高危人群，一种潜在的预防策略是对感染者进行根除治疗，但这一效果的确认尚需更长时间的随访。肥胖率持续上升，可能导致贲门癌发病率增加，尤其是在西方人群中，因此西方和亚洲人群都有必要密切监测这一结果。胃癌流行病学的这些变化预示着胃癌控制的新时代，有必要进一步监测描述性模式和风险因素。

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