Potish R A, Dehner L P, Haselow R E, Kim T H, Levitt S H, Nesbit M
Cancer. 1985 Oct 1;56(7):1534-7. doi: 10.1002/1097-0142(19851001)56:7<1534::aid-cncr2820560711>3.0.co;2-o.
From 1953 to 1975, 330 children received megavoltage for benign or malignant tumors. Fourteen subsequently developed second neoplasms. The 30-year cumulative incidence of second neoplasms was 9.6%. The incidence of second malignant neoplasms may be lower following megavoltage radiation than following orthovoltage radiation.