Wang Lulu, Fatemi Mostafa, Alizad Azra
Department of Engineering, School of Technology, Reykjavık University, Reykjavík, Iceland.
Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, MN, United States.
Front Oncol. 2024 Sep 3;14:1415859. doi: 10.3389/fonc.2024.1415859. eCollection 2024.
Hepatocellular Carcinoma (HCC), the most common primary liver cancer, is a significant contributor to worldwide cancer-related deaths. Various medical imaging techniques, including computed tomography, magnetic resonance imaging, and ultrasound, play a crucial role in accurately evaluating HCC and formulating effective treatment plans. Artificial Intelligence (AI) technologies have demonstrated potential in supporting physicians by providing more accurate and consistent medical diagnoses. Recent advancements have led to the development of AI-based multi-modal prediction systems. These systems integrate medical imaging with other modalities, such as electronic health record reports and clinical parameters, to enhance the accuracy of predicting biological characteristics and prognosis, including those associated with HCC. These multi-modal prediction systems pave the way for predicting the response to transarterial chemoembolization and microvascular invasion treatments and can assist clinicians in identifying the optimal patients with HCC who could benefit from interventional therapy. This paper provides an overview of the latest AI-based medical imaging models developed for diagnosing and predicting HCC. It also explores the challenges and potential future directions related to the clinical application of AI techniques.
肝细胞癌(HCC)是最常见的原发性肝癌,是全球癌症相关死亡的重要原因。各种医学成像技术,包括计算机断层扫描、磁共振成像和超声,在准确评估HCC和制定有效治疗方案方面发挥着关键作用。人工智能(AI)技术已显示出通过提供更准确和一致的医学诊断来支持医生的潜力。最近的进展导致了基于AI的多模态预测系统的开发。这些系统将医学成像与其他模态,如电子健康记录报告和临床参数相结合,以提高预测生物学特征和预后的准确性,包括与HCC相关的特征和预后。这些多模态预测系统为预测经动脉化疗栓塞和微血管侵犯治疗的反应铺平了道路,并可帮助临床医生识别能够从介入治疗中受益的最佳HCC患者。本文概述了为诊断和预测HCC而开发的最新基于AI的医学成像模型。它还探讨了与AI技术临床应用相关的挑战和潜在的未来方向。