State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Transl Vis Sci Technol. 2024 Sep 3;13(9):19. doi: 10.1167/tvst.13.9.19.
The purpose of this study was to investigate the choroidal characteristics of vortex vein (VV) drainage systems in healthy individuals using ultra-widefield optical coherence tomography angiography.
The mean choroidal thickness (ChT) and choroidal vascularity index (CVI) of each VV quadrant (24 × 20 mm2 scan mode; superotemporal [ST], superonasal [SN], inferonasal [IN], and inferotemporal [IT] quadrants) were calculated. Furthermore, intervortex venous anastomosis (IVA) was classified into temporal, superior, inferior, and nasal types.
A total of 207 healthy eyes were analyzed to find that the ST quadrant had the thickest choroidal layer and highest CVI (all P < 0.05). Among the four VV drainage quadrants, the mean ChT and CVI decreased in the sequence of ST, SN, IT, and IN (all P < 0.05). Moreover, men had a higher CVI than women in all VV quadrants (all P < 0.05). IVA was observed in all VV quadrants of 91 eyes (43.96%), and in the macular region of 33 eyes (15.94%).
The ST drainage system was identified as the preferred VV drainage route in healthy eyes. Among the four VV drainage quadrants, the drainage system adhered to the ST-SN-IT-IN order of descending perfusion. Furthermore, age- and sex-related differences were noted in the choroidal VV drainage systems of healthy eyes. Additionally, almost half of the healthy eyes had IVA in their choroidal vessel networks.
The VV drainage system may be considered a novel imaging biomarker for ocular diseases.
本研究旨在使用超广角光相干断层扫描血管造影术研究健康个体涡静脉（VV）引流系统的脉络膜特征。
计算每个 VV 象限（24×20mm2 扫描模式；上颞[ST]、上鼻侧[SN]、下鼻侧[IN]和下颞[IT]象限）的平均脉络膜厚度（ChT）和脉络膜血管指数（CVI）。此外，将涡静脉间吻合（IVA）分为颞、上、下和鼻型。
共分析了 207 只健康眼，发现 ST 象限的脉络膜层最厚，CVI 最高（均 P<0.05）。在四个 VV 引流象限中，平均 ChT 和 CVI 按 ST、SN、IT 和 IN 的顺序降低（均 P<0.05）。此外，男性在所有 VV 象限的 CVI 均高于女性（均 P<0.05）。在 91 只眼（43.96%）的所有 VV 象限和 33 只眼（15.94%）的黄斑区观察到 IVA。
ST 引流系统被认为是健康眼中首选的 VV 引流途径。在四个 VV 引流象限中，引流系统遵循 ST-SN-IT-IN 顺序，灌注逐渐减少。此外，健康眼的脉络膜 VV 引流系统存在与年龄和性别相关的差异。此外，约一半的健康眼在其脉络膜血管网络中存在 IVA。
杨昆
