Yadav Shikha, Singh Pratichi, Khan Javed, Singh Swetanshu
Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India.
Infect Disord Drug Targets. 2025;25(3):e18715265299763. doi: 10.2174/0118715265299763240818161040.
Pimples, blackheads, whiteheads, etc., are common types of acne that pop up on the skin each time, whenever dead cells and oils obstruct the outgrowth of hair from the hair follicle. It is very common to observe this condition in teenagers, but regardless of age, if the causing condition is met, acne can occur at any point in life. The characteristic feature of all types of acne is it starts with inflammation of the skin. These inflammatory marks (like black spots, pores, small scars, etc.) leave behind even when acne disappears. Plants like vegetables and flowers are naturally rich in different types of polyphenolic compounds called flavonoids. These flavonoids have various key functions, from guiding cell movement to maintaining oxidative pressure in the body. In this study, we discuss six types of flavonoids that have the potential to be used as medicine for the treatment of different kinds of skin breakouts. Moreover, the result of molecular docking of different proteins that have an association with acne is also discussed.
丘疹、黑头、白头等是常见的痤疮类型，每当死皮细胞和油脂阻碍毛囊毛发的生长时，就会出现在皮肤上。在青少年中观察到这种情况很常见，但无论年龄大小，只要满足引发条件，痤疮在人生的任何阶段都可能发生。所有类型痤疮的特征都是从皮肤炎症开始。即使痤疮消失，这些炎症痕迹（如黑点、毛孔、小疤痕等）仍会留下。蔬菜和花卉等植物天然富含称为类黄酮的不同类型多酚化合物。这些类黄酮具有多种关键功能，从引导细胞运动到维持体内氧化压力。在本研究中，我们讨论了六种有潜力用作治疗各种皮肤痘痘药物的类黄酮。此外，还讨论了与痤疮相关的不同蛋白质的分子对接结果。
