Marini M, Zunica G, Franceschi C
Proc Soc Exp Biol Med. 1985 Nov;180(2):246-57. doi: 10.3181/00379727-180-42172.
D-Ribose and deoxy-D-ribose inhibited DNA, RNA, and protein synthesis in a wide variety of cells (dividing and nondividing, normal and neoplastic, freely floating and substrate adhering, human and murine) at concentrations at which other monosaccharides have little or no effect. Inhibition was irreversible and proportional to the sugar concentration and time of contact. However, the first effects were seen only after 24 hr of incubation and progressed slowly to cell death. Whether the two sugars share the same mechanisms of action is not known. In any case, they deeply disturb metabolic processes in both dividing and nondividing cells.
D-核糖和脱氧-D-核糖在多种细胞（分裂和非分裂、正常和肿瘤、自由漂浮和附着于底物、人和鼠）中抑制DNA、RNA和蛋白质合成，其浓度下其他单糖几乎没有或没有影响。抑制是不可逆的，且与糖浓度和接触时间成正比。然而，最初的效应仅在孵育24小时后才出现，并缓慢发展至细胞死亡。这两种糖是否具有相同的作用机制尚不清楚。无论如何，它们都严重干扰了分裂和非分裂细胞中的代谢过程。
