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针灸及相关技术在肿瘤儿童和青少年患者管理中的疗效与安全性:一项系统评价

Efficacy and Safety of Acupuncture and Related Techniques in the Management of Oncological Children and Adolescent Patients: A Systematic Review.

作者信息

Martínez García Esther, Nishishinya Aquino M Betina, Cruz Martínez Ofelia, Ren Yiming, Xia Ruyu, Fei Yutong, Fernández-Jané Carles

机构信息

Integrative Pediatric Oncology Unit, Pediatric Cancer Center Barcelona, Sant Joan de Déu Children's Hospital, 08950 Barcelona, Spain.

Pediatric Neuro-Oncology, Pediatric Cancer Center Barcelona, Sant Joan de Déu Children's Hospital, 08950 Barcelona, Spain.

出版信息

Cancers (Basel). 2024 Sep 19;16(18):3197. doi: 10.3390/cancers16183197.

DOI:10.3390/cancers16183197
PMID:39335168
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11429796/
Abstract

/: Oncology acupuncture is emerging as a complementary treatment in pediatric cancer care centers. It is valued for its potential to manage symptoms associated with cancer and treatment toxicities without increasing polypharmacy. The aim of this review is to evaluate the efficacy and safety of acupuncture and related techniques in alleviating symptoms of cancer treatment in pediatric oncology patients. : A comprehensive search was conducted across nine databases, including PubMed, Cochrane Library, and CNKI, up to June 2023. Inclusion criteria focused on randomized and quasi-randomized controlled trials involving pediatric oncology patients undergoing needle acupuncture or related techniques. Study selection and data extraction were independently performed by pairs of authors. Results were analyzed narratively, and meta-analysis was performed when possible. : Results suggest that acupuncture may help manage symptoms such as nausea and vomiting in pediatric oncology patients. However, the quality of evidence was generally low, and further research is required to substantiate these findings. : Acupuncture shows promising results as a complementary treatment for reducing nausea and vomiting in pediatric oncology. However, current evidence is insufficient to draw conclusions for other outcomes, such as the number of vomiting episodes, reduction in antiemetic medication use, or fatigue. High-quality, rigorously designed studies are necessary to better understand the clinical relevance and safety of acupuncture in this vulnerable population.

摘要

/: 肿瘤针灸正逐渐成为儿科癌症护理中心的一种辅助治疗方法。它因其在不增加多种药物联合使用的情况下,有管理与癌症及治疗毒性相关症状的潜力而受到重视。本综述的目的是评估针灸及相关技术在缓解儿科肿瘤患者癌症治疗症状方面的疗效和安全性。: 截至2023年6月,对包括PubMed、Cochrane图书馆和中国知网在内的九个数据库进行了全面检索。纳入标准集中在涉及接受针刺或相关技术的儿科肿瘤患者的随机和半随机对照试验。研究选择和数据提取由作者对独立进行。对结果进行叙述性分析,并在可能的情况下进行荟萃分析。: 结果表明,针灸可能有助于管理儿科肿瘤患者的恶心和呕吐等症状。然而,证据质量普遍较低,需要进一步研究来证实这些发现。: 针灸作为减少儿科肿瘤恶心和呕吐的辅助治疗显示出有前景的结果。然而,目前的证据不足以就其他结果得出结论,如呕吐发作次数、止吐药物使用减少或疲劳。需要高质量、设计严谨的研究来更好地了解针灸在这一脆弱人群中的临床相关性和安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d53/11429796/a58eb64398a2/cancers-16-03197-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d53/11429796/191a6acab3e9/cancers-16-03197-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d53/11429796/a58eb64398a2/cancers-16-03197-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d53/11429796/191a6acab3e9/cancers-16-03197-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d53/11429796/a58eb64398a2/cancers-16-03197-g002.jpg

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Integrative Medicine for Pain Management in Oncology: Society for Integrative Oncology-ASCO Guideline.肿瘤学中的疼痛管理整合医学:肿瘤整合医学学会-美国临床肿瘤学会指南。
J Clin Oncol. 2022 Dec 1;40(34):3998-4024. doi: 10.1200/JCO.22.01357. Epub 2022 Sep 19.
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Safety of Complementary and Alternative Medicine (CAM) treatment among children and young adults who suffer from adverse effects of conventional cancer treatment: A systematic review.
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Integr Cancer Ther. 2022 Jan-Dec;21:15347354221105563. doi: 10.1177/15347354221105563.
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The Effects of Acupressure in the Prevention of Nausea and Vomiting Related to Chemotherapy in Children: A Randomized Double-Blinded Placebo-Controlled Study. acupressure 预防儿童化疗相关性恶心呕吐的效果:一项随机双盲安慰剂对照研究。
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