School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410000, China.
School of Pharmaceutical Science, Hunan University of Medicine, Huaihua 418000, China.
Molecules. 2024 Sep 21;29(18):4486. doi: 10.3390/molecules29184486.
Saponins are an important class of active components in Chinese herbal medicines (CHMs), which are present in large quantities in , , , etc., and have immune regulation, anti-tumor, anti-inflammatory, anti-cardiovascular disease, and hypoglycemic activities. Storage and processing are essential processes in the production process of CHMs which affect the stability of saponin components and then reduce the medicinal and economic value. Therefore, it is of great importance to investigate the effects of storage and processing conditions on the content of saponin components in CHMs. In this paper, the effects of various storage and processing factors, including temperature, pH, enzymes, meta lions, extraction methods, etc., on the saponin content of CHMs are investigated and the underlying mechanisms for the quantitative changes of saponin are summarized. These findings may provide technical guidance for the production and processing of saponin-rich CHMs.
皂苷是中草药（CHM）中的一类重要活性成分，大量存在于 、 、 等中，具有免疫调节、抗肿瘤、抗炎、抗心血管疾病和降血糖作用。储存和加工是 CHM 生产过程中的重要环节，会影响皂苷成分的稳定性，从而降低药用和经济价值。因此，研究储存和加工条件对 CHM 中皂苷成分含量的影响具有重要意义。本文综述了温度、pH 值、酶、金属离子、提取方法等各种储存和加工因素对 CHM 中皂苷含量的影响，并总结了皂苷定量变化的潜在机制。这些发现可能为富含皂苷的 CHM 的生产和加工提供技术指导。
