Gao Ying, Liu Shangbin, Xu Huifang, Wang Ying, Xu Gang, Hu Fan, Zhang Jiechen, Cai Yong
Public Health Department, Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Vaccines (Basel). 2024 Sep 3;12(9):1009. doi: 10.3390/vaccines12091009.
Vaccine hesitancy is a significant barrier to achieving high vaccination rates, particularly among men who have sex with men (MSM), a group at increased risk for Mpox. This study aimed to develop and validate a Mpox vaccine hesitancy scale specifically tailored for Chinese MSM, grounded in the protection motivation theory (PMT).
An online survey through snowball sampling was conducted from October 2023 to March 2024, collecting 2403 valid responses across six representative regions in China. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were conducted to evaluate the scale's construct validity, while reliability was assessed using Cronbach's α coefficient. The predictive validity of the scale was analyzed using Receiver Operating Characteristic (ROC) analysis.
EFA ultimately retained 22 items in the Mpox vaccination scale and identified four distinct dimensions: Maladaptive Rewards (seven items), Self-efficacy (seven items), Response Efficacy (four items), and Response Costs (four items). These dimensions were confirmed by CFA, which demonstrated satisfactory model fit indices (χ²/df = 4.382, RMSEA = 0.053, SRMR = 0.048, GFI = 0.935, CFI = 0.967, NFI = 0.958, TLI = 0.963, and IFI =0.967). All indices were within acceptable ranges. The scale exhibited good internal consistency, with a Cronbach's alpha of 0.906, and strong content validity, with an S-CVI/Ave of 0.952. The scale's predictive accuracy was evaluated using Receiver Operating Characteristic (ROC) analysis. When used to evaluate the scale's predictive accuracy, it yielded an area under the curve (AUC) of 0.854 after adjustments, indicating good predictive ability between high and low hesitancy.
This scale provides a reliable and valid tool for assessing Mpox vaccine hesitancy among MSM and can be used to gauge Mpox vaccination intention within this group.
疫苗犹豫是实现高疫苗接种率的重大障碍，尤其是在男男性行为者（MSM）中，这一群体感染猴痘的风险增加。本研究旨在基于保护动机理论（PMT）开发并验证一种专门为中国男男性行为者量身定制的猴痘疫苗犹豫量表。
2023年10月至2024年3月通过雪球抽样进行了一项在线调查，在中国六个代表性地区收集了2403份有效回复。进行探索性因素分析（EFA）和验证性因素分析（CFA）以评估量表的结构效度，同时使用克朗巴哈α系数评估信度。使用受试者工作特征（ROC）分析来分析量表的预测效度。
探索性因素分析最终在猴痘疫苗接种量表中保留了22个项目，并确定了四个不同维度：适应不良奖励（7个项目）、自我效能感（7个项目）、反应效能（4个项目）和反应成本（4个项目）。这些维度通过验证性因素分析得到确认，该分析显示出令人满意的模型拟合指数（χ²/df = 4.382，RMSEA = 0.053，SRMR = 0.048，GFI = 0.935，CFI = 0.967，NFI = 0.958，TLI = 0.963，IFI = 0.967）。所有指数均在可接受范围内。该量表表现出良好的内部一致性，克朗巴哈α系数为0.906，内容效度良好，S-CVI/Ave为 = 0.952。使用受试者工作特征（ROC）分析评估量表的预测准确性。在用于评估量表的预测准确性时，调整后曲线下面积（AUC）为0.854，表明在高犹豫和低犹豫之间具有良好的预测能力。
该量表为评估男男性行为者对猴痘疫苗的犹豫程度提供了一种可靠且有效的工具，可用于衡量该群体内的猴痘疫苗接种意愿。
