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激光治疗痤疮瘢痕疗效的回顾性分析

Retrospective Analysis of the Effectiveness of Laser Therapy in the Treatment of Acne Scarring.

作者信息

Maiti Niladri, Benedicenti Stefano, Shashank Chapala, Venkateshwar Gokul, Srivastava Amartya P, Tate Jignesh, Tiwari Rahul

机构信息

School of Dentistry, Central Asian University, Tashkent, Uzbekistan.

Department of Surgical and Diagnostic Sciences, University of Genoa, Genoa, Italy.

出版信息

J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2413-S2415. doi: 10.4103/jpbs.jpbs_240_24. Epub 2024 Jul 31.

Abstract

OBJECTIVE

This retrospective analysis aimed to estimate the efficiency of laser therapy in the management of acne scarring, assessing changes in scar severity, patient satisfaction, and adverse events.

METHODS

A cohort of 150 subjects with clinically diagnosed acne scarring who underwent laser therapy. Data were extracted from electronic medical records, and baseline characteristics, scar types, and management parameters were analyzed. Outcome measures included changes in scar severity scores, patient-reported satisfaction, and documentation of adverse events. Statistical analyses were conducted using appropriate methods, with sub-group analyses based on scar type and laser modality.

RESULTS

Following laser therapy, a statistically significant decrease in scar severity scores was seen across all scar types ( < 0.05). Patient satisfaction was high, with 75% reporting significant improvement. Adverse events were mild and transient, including erythema and post-inflammatory hyperpigmentation. Sub-group analyses did not reveal significant differences in management outcomes based on scar type or laser modality.

CONCLUSION

Laser therapy demonstrates effectiveness in reducing acne scarring with a favorable safety profile. The research supports its role as a versatile management modality for diverse scar presentations, emphasizing the need for further research to optimize protocols and explore combination therapies.

摘要

目的

本回顾性分析旨在评估激光治疗痤疮瘢痕的效果,评估瘢痕严重程度的变化、患者满意度及不良事件。

方法

对150例临床诊断为痤疮瘢痕且接受激光治疗的受试者进行队列研究。从电子病历中提取数据,并分析基线特征、瘢痕类型及治疗参数。观察指标包括瘢痕严重程度评分的变化、患者报告的满意度及不良事件记录。采用适当方法进行统计分析,并根据瘢痕类型和激光治疗方式进行亚组分析。

结果

激光治疗后,所有瘢痕类型的瘢痕严重程度评分均有统计学意义的下降(<0.05)。患者满意度较高,75%的患者报告有显著改善。不良事件轻微且短暂,包括红斑和炎症后色素沉着。亚组分析未发现基于瘢痕类型或激光治疗方式的治疗效果存在显著差异。

结论

激光治疗在减轻痤疮瘢痕方面显示出有效性,且安全性良好。该研究支持其作为多种瘢痕表现的通用治疗方式的作用,强调需要进一步研究以优化治疗方案并探索联合治疗。

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本文引用的文献

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Acne scarring treatment using skin needling.皮肤针刺治疗痤疮瘢痕。
Clin Exp Dermatol. 2009 Dec;34(8):874-9. doi: 10.1111/j.1365-2230.2009.03291.x. Epub 2009 May 22.
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Subcision for acne scarring: technique and outcomes in 40 patients.痤疮瘢痕的皮下分离术:40例患者的技术与疗效
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