甲状腺功能减退患者与非甲状腺功能减退患者口腔扁平苔藓的患病率
Prevalence of Oral Lichen Planus in Patients with Hypothyroidism Versus Nonhypothyroidism.
作者信息
Bansal Priyanka Vinod, Raj Kavita, Gupta Neha, Dwivedi Dhara, Sethi Ashish, Prabhakar Nitin, Makkad Ramanpal Singh
机构信息
MDS Prosthodontics and Oral Implantology, Private Practise, Wakad, Pune, India.
Department of Dentistry, Gandhi Medical College, Bhopal, MP, India.
出版信息
J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2159-S2161. doi: 10.4103/jpbs.jpbs_111_24. Epub 2024 May 1.
BACKGROUND
A chronic inflammatory illness known as oral lichen planus (OLP) affects approximately 1-2% of adults, with middle-aged women having a higher prevalence than men. One clinical endocrine condition that primary care doctors frequently see is hypothyroidism.
AIM
To compare the prevalence of OLP among individuals with a previous diagnosis of hypothyroidism against those without hypothyroidism.
METHODS AND MATERIALS
A total of 1200 patients were included in this study. As per their medical reports, 600 patients included were found to have hypothyroidism. The rest 600 patients did not have hypothyroidism. All the patients underwent clinical examination and cases of OLP were identified according to the criteria of diagnosis of OLP.
RESULTS
Twenty (3.45%) study participants with hypothyroidism were found to have OLP. Eight (1.34%) study participants without hypothyroidism were found to have OLP of 2.37 (confidence interval: 0.91-6.23) and showed that the frequency of lichen planus in study participants with hypothyroidism was 2.37 times greater than that without hypothyroidism.
CONCLUSION
Prevalence of lichen planus in persons with hypothyroidism was greater than that without hypothyroidism.
背景
口腔扁平苔藓（OLP）是一种慢性炎症性疾病，影响约1%-2%的成年人，中年女性的患病率高于男性。原发性甲状腺功能减退症是基层医疗医生经常见到的一种临床内分泌疾病。
目的
比较既往诊断为甲状腺功能减退症的个体与未患甲状腺功能减退症的个体中OLP的患病率。
方法和材料
本研究共纳入1200例患者。根据他们的医学报告，发现其中600例患者患有甲状腺功能减退症。其余600例患者没有甲状腺功能减退症。所有患者均接受临床检查，并根据OLP的诊断标准确定OLP病例。
结果
发现20例（3.45%）患有甲状腺功能减退症的研究参与者患有OLP。8例（1.34%）没有甲状腺功能减退症的研究参与者患有OLP，比值比为2.37（置信区间：0.91-6.23），表明患有甲状腺功能减退症的研究参与者中扁平苔藓的发生率比没有甲状腺功能减退症的参与者高2.37倍。
结论
甲状腺功能减退症患者中扁平苔藓的患病率高于未患甲状腺功能减退症的患者。
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