Papadiochou Aggeliki, Diamanti Athina, Metallinou Dimitra, Georgakopoulou Vasiliki E, Taskou Chrysoula, Kagkouras Iraklis, Sarantaki Antigoni
Department of Midwifery, University of West Attica, Athens, GRC.
Department of Pathophysiology/Pulmonology, Laiko General Hospital, Athens, GRC.
Cureus. 2024 Aug 30;16(8):e68221. doi: 10.7759/cureus.68221. eCollection 2024 Aug.
Climate change has emerged as a significant global health challenge, with growing evidence linking environmental factors to adverse reproductive health outcomes. The primary objective of this review is to assess the effects of climate change-driven environmental factors, such as air pollution and temperature extremes, on reproductive health outcomes, including fertility rates, miscarriage, preterm birth, and congenital anomalies. A comprehensive search of PubMed, Google Scholar, and Web of Science was conducted until July 2024. Studies included in the review were observational, experimental, and randomized controlled trials that reported quantitative data on reproductive outcomes in relation to climate-related environmental exposures. A total of 49 studies were selected for qualitative synthesis. The review found that increased exposure to particulate matter (PM2.5), extreme temperatures, and proximity to traffic were consistently associated with reduced fertility, increased risks of miscarriage, preterm birth, and low birth weight. Adverse effects were particularly pronounced among vulnerable populations, such as pregnant women of lower socioeconomic status and those living in disaster-prone areas. The studies also highlighted potential transgenerational effects, with prenatal exposure to environmental stressors influencing the long-term health of offspring. The findings underscore the urgent need for public health interventions and policies to mitigate environmental exposures that negatively impact reproductive health. Future research should focus on longitudinal and interventional studies to establish causal relationships and inform effective public health strategies.
气候变化已成为一项重大的全球健康挑战,越来越多的证据表明环境因素与不良生殖健康结果之间存在关联。本综述的主要目的是评估气候变化驱动的环境因素,如空气污染和极端温度,对生殖健康结果的影响,包括生育率、流产、早产和先天性异常。对PubMed、谷歌学术和科学网进行了全面检索,直至2024年7月。纳入本综述的研究包括观察性、实验性和随机对照试验,这些试验报告了与气候相关环境暴露相关的生殖结果的定量数据。共选择了49项研究进行定性综合分析。综述发现,接触细颗粒物(PM2.5)增加、极端温度以及靠近交通区域与生育率降低、流产、早产和低出生体重风险增加始终相关。在弱势群体中,如社会经济地位较低的孕妇和生活在易受灾地区的孕妇,不良影响尤为明显。研究还强调了潜在的跨代效应,即产前接触环境应激源会影响后代的长期健康。这些发现强调了迫切需要公共卫生干预措施和政策,以减轻对生殖健康产生负面影响的环境暴露。未来的研究应侧重于纵向和干预性研究,以建立因果关系并为有效的公共卫生策略提供依据。