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法国西部单克隆丙种球蛋白病调查:IgM的发病率及意外的高频率

Survey of monoclonal gammopathy in western France: incidence and unexpected high frequency of IgM.

作者信息

Hurez D, Youinou P, Gombert J, Preud'Homme J L

出版信息

Immunology. 1985 Nov;56(3):557-60.

Abstract

The class distribution of 4193 monoclonal gammopathies (MG), detected over approximately 10 years in western France (WF), was compared to that established by a compilation of twenty-seven series from the literature. Several points emerged from this study: the incidence of the light chain MG (4.8%) was slightly lower than commonly observed (6.0%), the number of double MG higher (4.2%) than elsewhere (1-3%) and the IgM-MG much more frequent (33.0%) than anywhere else (16.2%).

摘要

在法国西部(WF)约10年期间检测出的4193例单克隆丙种球蛋白病(MG)的类别分布,与从文献中汇编的27个系列所确定的分布进行了比较。这项研究得出了几个要点:轻链MG的发病率(4.8%)略低于通常观察到的发病率(6.0%),双MG的数量(4.2%)高于其他地方(1%-3%),并且IgM-MG比其他任何地方都更常见(33.0%)(16.2%)。

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本文引用的文献

1
FAMILIAL OCCURRENCE OF PATHOLOGICAL SERUM-PROTEINS OF DIFFERENT GAMMA-GLOBULIN GROUPS.
Lancet. 1965 Aug 21;2(7408):369-70. doi: 10.1016/s0140-6736(65)90344-2.
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High incidence of myelomatosis in North-East Scotland.苏格兰东北部骨髓瘤发病率高。
Scott Med J. 1973 May;18(3):75-7. doi: 10.1177/003693307301800302.
10
["Essential" dysglobulinemia in aged subjects].
Nouv Rev Fr Hematol. 1965 Sep-Oct;5(5):729-38.

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