Świątkowski Filip, Lambrinow Jakub, Górnicki Tomasz, Jurga Marta, Chabowski Mariusz
Department of Surgery, 4th Military Clinical Hospital, Wroclaw, 50-981, Poland.
Division of Anaesthesiologic and Surgical Nursing, Department of Nursing and Obstetrics, Faculty of Health Science, Wroclaw Medical University, Wroclaw, 51-618, Poland.
Cancer Manag Res. 2024 Sep 27;16:1293-1303. doi: 10.2147/CMAR.S478179. eCollection 2024.
Due to the increasing number of cases and the levels of mortality, colorectal cancer is still a major health problem. Therefore, the growing interest in the quality of life of patients and the assessment of the quality of life of patients with colorectal cancer seems to be particularly important. The aim of the study was to investigate and determine factors that have a significant impact on the QoL of patients who were diagnosed with colorectal cancer that was surgically treated in the Surgical Department of the 4th Military Clinical Hospital in Wroclaw.
102 respondents were enrolled into the study. The QLQ-C30, QLQ-CR29 as well as an original questionnaire regarding the socioeconomic factors were used for the assessment. The information was supplemented with patients' clinical data.
According to the QLQ-C30 questionnaire the average QoL of the respondents was 55%. Factors such as male gender, younger age, higher BMI, no significant weight loss, living with family, lower level of education and being professionally active have significant positive impact on QoL. In contrary, patients with more advanced and malignant cancer with tumor located in the right half of the colon had worse QoL. The particular domains of QoL influenced by these factors were also identified. Determining these factors will allow for more effective treatment, for the shortening of the hospitalization and finally for the reduction of the costs.
The better QoL of the patients with colorectal cancer treated surgically showed younger men, living with family and with the support from close people, professionally active, with primary level of education, and without significant weight loss, ie less than 5% of body weight in the last 6 months. Moreover, patients with cancer located in the left colon, at a lower stage, with a lower grading demonstrated a better QoL.
由于病例数量和死亡率不断上升，结直肠癌仍然是一个重大的健康问题。因此，对患者生活质量的关注度日益提高，评估结直肠癌患者的生活质量显得尤为重要。本研究的目的是调查并确定对在弗罗茨瓦夫第四军事临床医院外科接受手术治疗的结直肠癌患者生活质量有重大影响的因素。
102名受访者参与了本研究。使用QLQ-C30、QLQ-CR29以及一份关于社会经济因素的原始问卷进行评估。信息补充了患者的临床数据。
根据QLQ-C30问卷，受访者的平均生活质量为55%。男性、年龄较小、体重指数较高、无明显体重减轻、与家人同住、教育程度较低和职业活跃等因素对生活质量有显著的积极影响。相反，癌症更晚期且恶性程度高、肿瘤位于结肠右半部分的患者生活质量较差。还确定了受这些因素影响的生活质量的具体领域。确定这些因素将有助于更有效的治疗，缩短住院时间并最终降低成本。
接受手术治疗的结直肠癌患者生活质量较好的情况表现为：年轻男性、与家人同住且有亲人支持、职业活跃、小学教育程度、无明显体重减轻，即过去6个月内体重减轻少于体重的5%。此外，癌症位于左半结肠、分期较低、分级较低的患者生活质量较好。
