Advanced Bio and Healthcare Materials Research Division, Korea Institute of Materials Science (KIMS), Changwon, 51508, South Korea.
School of Biomedical Engineering, College of Health Science, Korea University, Seoul, 02841, South Korea; Interdisciplinary Program in Precision Public Health, Korea University, Seoul, 02841, South Korea.
Biomaterials. 2025 Mar;314:122865. doi: 10.1016/j.biomaterials.2024.122865. Epub 2024 Sep 27.
Devices used for diagnosing disease are often large, expensive, and require operation by trained professionals, which can result in delayed diagnosis and missed opportunities for timely treatment. However, wearable devices are being recognized as a new approach to overcoming these difficulties, as they are small, affordable, and easy to use. Recent advancements in wearable technology have made monitoring information possible from the surface of organs like the skin and eyes, enabling accurate diagnosis of the user's internal status. In this review, we categorize the body's organs into external (e.g., eyes, oral cavity, neck, and skin) and internal (e.g., heart, brain, lung, stomach, and bladder) organ systems and introduce recent developments in the materials and designs of wearable electronics, including electrochemical and electrophysiological sensors applied to each organ system. Further, we explore recent innovations in wearable electronics for monitoring of deep internal organs, such as the heart, brain, and nervous system, using ultrasound, electrical impedance tomography, and temporal interference stimulation. The review also addresses the current challenges in wearable technology and explores future directions to enhance the effectiveness and applicability of these devices in medical diagnostics. This paper establishes a framework for correlating the design and functionality of wearable electronics with the physiological characteristics and requirements of various organ systems.
用于诊断疾病的设备通常体积大、价格昂贵,并且需要经过专业培训的人员操作,这可能导致诊断延误和错失及时治疗的机会。然而,可穿戴设备正被视为克服这些困难的一种新方法,因为它们体积小、价格实惠且易于使用。可穿戴技术的最新进展使得可以从皮肤和眼睛等器官的表面监测信息,从而能够准确诊断用户的内部状况。在这篇综述中,我们将人体器官分为外部(例如,眼睛、口腔、颈部和皮肤)和内部(例如,心脏、大脑、肺、胃和膀胱)器官系统,并介绍了可穿戴电子产品在材料和设计方面的最新进展,包括应用于每个器官系统的电化学和电生理传感器。此外,我们还探讨了可穿戴电子产品在监测深部内部器官(如心脏、大脑和神经系统)方面的最新创新,这些创新使用了超声波、电阻抗断层成像和时间干涉刺激。本文还讨论了可穿戴技术当前面临的挑战,并探讨了未来的发展方向,以提高这些设备在医疗诊断中的有效性和适用性。该文建立了一个将可穿戴电子产品的设计和功能与各种器官系统的生理特征和要求相关联的框架。