Department of Dermatology, The Second Hospital of Dalian Medical University, Dalian, 116023, China.
Department of Food Nutrition and Safety, Dalian Medical University, Dalian, 116044, China.
Sci Rep. 2024 Oct 3;14(1):22997. doi: 10.1038/s41598-024-73219-9.
Skin cancer is a common disease resulting from genetic defects, and early detection is critical to improve treatment outcomes. Diagnostic programs that use computer aid especially those that use supervised learning are very useful in early diagnosis of skin cancer. This research therefore presents a new approach that integrates optimization methods with supervised learning to improve skin cancer diagnosis using machine vision approach. The presented method is initiated by data pre-processing that involves the removal of unnecessary data. Then, to segment the images, a combination of K-means clustering and social spider optimization technique is employed. The region of interest is then extracted from the segmented image and from this region a convolutional neural network extracts the significant features. To enhance the classification performance as compared with the standard classifiers, this research introduces a new concept of error correcting output codes coupled with a weighted Hamming distance in the group of gamma classifiers. The ability of the proposed approach in segmentation of skin lesions and classifying them was tested using samples from the ISIC-2017 and ISIC-2016 databases. The introduced method obtained state-of-the-art accuracy on both datasets (ISIC-2016: 97.10%, ISIC-2017: 95.17%). In particularly, the accuracy of the introduced approach for both these databases is at least 1.17% higher than the compared methods. This proves the high performance of the suggested method based on the usage of the convolutional neural networks for feature extraction and gamma classifiers with error correcting output codes for classification in skin cancer detection.
皮肤癌是一种常见的遗传缺陷疾病,早期发现对于改善治疗效果至关重要。使用计算机辅助的诊断程序,特别是那些使用监督学习的程序,对于皮肤癌的早期诊断非常有用。因此,本研究提出了一种新的方法,该方法将优化方法与监督学习相结合,通过机器视觉方法来提高皮肤癌的诊断效果。该方法首先进行数据预处理,包括去除不必要的数据。然后,采用 K-均值聚类和社交蜘蛛优化技术对图像进行分割。接着,从分割后的图像中提取感兴趣的区域,然后从该区域中使用卷积神经网络提取显著特征。为了提高与标准分类器相比的分类性能,本研究引入了纠错输出码的新概念,并在伽马分类器组中使用加权汉明距离。使用来自 ISIC-2017 和 ISIC-2016 数据库的样本测试了所提出方法在皮肤病变分割和分类中的能力。该方法在两个数据集(ISIC-2016:97.10%,ISIC-2017:95.17%)上都取得了最先进的准确性。特别是,该方法在这两个数据库上的准确性至少比比较方法高 1.17%。这证明了基于卷积神经网络进行特征提取和使用纠错输出码的伽马分类器进行分类的建议方法在皮肤癌检测中的高性能。