Honda Maya, Sigmund Eric E, Le Bihan Denis, Pinker Katja, Clauser Paola, Karampinos Dimitrios, Partridge Savannah C, Fallenberg Eva, Martincich Laura, Baltzer Pascal, Mann Ritse M, Camps-Herrero Julia, Iima Mami
Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Department of Diagnostic Radiology, Kansai Electric Power Hospital, Osaka, Japan.
Eur Radiol. 2025 Apr;35(4):2130-2140. doi: 10.1007/s00330-024-11010-0. Epub 2024 Oct 8.
This study by the EUSOBI International Breast Diffusion-weighted Imaging (DWI) working group aimed to evaluate the current and future applications of advanced DWI in breast imaging.
A literature search and a comprehensive survey of EUSOBI members to explore the clinical use and potential of advanced DWI techniques and a literature search were involved. Advanced DWI approaches such as intravoxel incoherent motion (IVIM), diffusion kurtosis imaging (DKI), and diffusion tensor imaging (DTI) were assessed for their current status and challenges in clinical implementation.
Although a literature search revealed an increasing number of publications and growing academic interest in advanced DWI, the survey revealed limited adoption of advanced DWI techniques among EUSOBI members, with 32% using IVIM models, 17% using non-Gaussian diffusion techniques for kurtosis analysis, and only 8% using DTI. A variety of DWI techniques are used, with IVIM being the most popular, but less than half use it, suggesting that the study identified a gap between the potential benefits of advanced DWI and its actual use in clinical practice.
The findings highlight the need for further research, standardization and simplification to transition advanced DWI from a research tool to regular practice in breast imaging. The study concludes with guidelines and recommendations for future research directions and clinical implementation, emphasizing the importance of interdisciplinary collaboration in this field to improve breast cancer diagnosis and treatment.
Advanced DWI in breast imaging, while currently in limited clinical use, offers promising improvements in diagnosis, staging, and treatment monitoring, highlighting the need for standardized protocols, accessible software, and collaborative approaches to promote its broader integration into routine clinical practice.
Increasing number of publications on advanced DWI over the last decade indicates growing research interest. EUSOBI survey shows that advanced DWI is used primarily in research, not extensively in clinical practice. More research and standardization are needed to integrate advanced DWI into routine breast imaging practice.
由EUSOBI国际乳腺扩散加权成像（DWI）工作组开展的这项研究旨在评估先进DWI在乳腺成像中的当前及未来应用。
进行文献检索，并对EUSOBI成员进行全面调查，以探索先进DWI技术的临床应用及潜力，同时进行文献检索。评估了诸如体素内不相干运动（IVIM）、扩散峰度成像（DKI）和扩散张量成像（DTI）等先进DWI方法在临床应用中的现状及面临的挑战。
尽管文献检索显示有关先进DWI的出版物数量不断增加，学术关注度也日益提高，但调查显示EUSOBI成员中先进DWI技术的应用有限，32%使用IVIM模型，17%使用非高斯扩散技术进行峰度分析，仅8%使用DTI。使用了多种DWI技术，其中IVIM最受欢迎，但使用它的比例不到一半，这表明该研究发现了先进DWI的潜在益处与其在临床实践中的实际应用之间存在差距。
研究结果凸显了进一步开展研究、实现标准化和简化的必要性，以便将先进DWI从一种研究工具转变为乳腺成像的常规实践。该研究最后给出了未来研究方向和临床应用的指南及建议，强调了该领域跨学科合作对于改善乳腺癌诊断和治疗的重要性。
乳腺成像中的先进DWI目前临床应用有限，但在诊断、分期和治疗监测方面有望带来改善，这凸显了需要标准化方案、易用软件以及协作方法，以促进其更广泛地融入常规临床实践。
过去十年中关于先进DWI的出版物数量不断增加，表明研究兴趣日益浓厚。EUSOBI调查显示，先进DWI主要用于研究，在临床实践中未得到广泛应用。需要更多研究和标准化，以将先进DWI纳入常规乳腺成像实践。
