Awashra Ameer, Sawaftah Zaid, Odah Ali Bani, Sawafta Ahmed, Khatib Amer, Dababat Huthayfa, Yasin Anas, Khamaysa Jehad, Daraghmeh Muath
Department of Medicine, An Najah National University, Nablus P606, Palestine.
Department of Surgery, Tubas Turkish Governmental Hospital, Tubas P606, Palestine.
J Surg Case Rep. 2024 Oct 8;2024(10):rjae633. doi: 10.1093/jscr/rjae633. eCollection 2024 Oct.
Angiosarcoma, a rare endothelial cell tumor, accounts for < 2% of all sarcomas, typically affecting elderly patients. We present the case of a 62-year-old male with a history of hypertension and ischemic heart disease, who initially presented with severe lower back pain. Subsequent imaging revealed a ruptured splenic lesion and multiple liver lesions, leading to a diagnosis of stage 4 angiosarcoma. Post-splenectomy, the patient exhibited pathological vertebral fractures and elevated liver function tests, consistent with metastatic disease. Despite aggressive surgical intervention and supportive care, the patient's condition remained critical. The treatment plan included palliative chemotherapy, spine radiotherapy, and ongoing pain management, with close monitoring of disease progression and response to therapy. This case describes the diagnostic challenges and poor prognosis associated with metastatic angiosarcoma.
血管肉瘤是一种罕见的内皮细胞肿瘤，占所有肉瘤的比例不到2%，通常影响老年患者。我们报告了一例62岁男性病例，该患者有高血压和缺血性心脏病史，最初表现为严重的下背部疼痛。随后的影像学检查发现脾脏病变破裂和多个肝脏病变，最终诊断为4期血管肉瘤。脾切除术后，患者出现病理性椎体骨折，肝功能检查结果升高，符合转移性疾病表现。尽管进行了积极的手术干预和支持治疗，但患者的病情仍然危急。治疗方案包括姑息性化疗、脊柱放疗和持续的疼痛管理，并密切监测疾病进展和对治疗的反应。本病例描述了转移性血管肉瘤相关的诊断挑战和不良预后。
