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针对侵犯肠系膜上静脉的胰腺导管腺癌的根治性治疗。

Curative intent treatment for pancreatic duct adenocarcinoma invade superior mesenteric vein.

作者信息

Hoang Ha Pham, Thanh Dung Le, Huu Khuyen Pham, Quang Thai Pham, Ba An Pham, Quang Duy Ngo

机构信息

Department of Digestive Surgery, Viet Duc University Hospital, Vietnam.

Department of Surgery, University of Medicine and Pharmacy (VNU-UMP), Vietnam National University, Hanoi, Vietnam.

出版信息

Radiol Case Rep. 2024 Sep 24;19(12):6265-6268. doi: 10.1016/j.radcr.2024.09.033. eCollection 2024 Dec.

DOI:10.1016/j.radcr.2024.09.033
PMID:39387005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11462047/
Abstract

Pancreatic duct adenocarcinoma (PDAC) accounts for about 85-90% of all solid pancreatic tumors, which is well-known for poor prognosis and high morbidity. Despite the massive advent of chemotherapy and radiotherapy in recent years, surgical removal is still considered the cornerstone management option in this situation. Pancreaticoduodenectomy or Whipple procedure is generally contraindicated in metastasis or tumors that encase more than 50% of vessels. Vascular reconstruction is a state-of-the-art technique which requires the remarkable involvement of vascular experts in the setting of PDAC-invading vessels. In this article, we present an exceptional case of a 38-year-old male patient who underwent radical resection for advanced pancreatic cancer with superior mesenteric vein reconstruction by a great saphenous vein.

摘要

胰腺导管腺癌(PDAC)约占所有胰腺实性肿瘤的85%-90%,以预后差和高发病率而闻名。尽管近年来化疗和放疗大量出现,但手术切除仍是这种情况下的基石治疗选择。胰十二指肠切除术或惠普尔手术通常在发生转移或肿瘤包绕超过50%血管时为禁忌。血管重建是一项先进技术,在PDAC侵犯血管的情况下需要血管专家的显著参与。在本文中,我们介绍了一例特殊病例,一名38岁男性患者因晚期胰腺癌接受了根治性切除,并采用大隐静脉进行了肠系膜上静脉重建。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4093/11462047/d8a97517571f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4093/11462047/fa7a9985cdda/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4093/11462047/d8a97517571f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4093/11462047/fa7a9985cdda/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4093/11462047/d8a97517571f/gr2.jpg

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本文引用的文献

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Surgical resection of metastatic pancreatic cancer: is it worth it?-a 15-year experience at a single Chinese center.转移性胰腺癌的手术切除:是否值得?——中国一家中心的15年经验
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Ann Surg. 2021 Mar 1;273(3):579-586. doi: 10.1097/SLA.0000000000003301.
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Epidemiology of Pancreatic Cancer: Global Trends, Etiology and Risk Factors.胰腺癌的流行病学:全球趋势、病因及风险因素
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Preoperative drainage for perihilar cholangiocarcinoma.肝门部胆管癌的术前引流
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Added value of CA19-9 response in predicting resectability of locally advanced pancreatic cancer following induction chemotherapy.CA19-9反应在预测局部晚期胰腺癌诱导化疗后可切除性方面的附加价值。
HPB (Oxford). 2018 Jul;20(7):605-611. doi: 10.1016/j.hpb.2018.01.001. Epub 2018 Feb 21.
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Pancreatoduodenectomy combined with portal-superior mesenteric vein resection and reconstruction with interposition grafts for cancer: a meta-analysis.胰十二指肠切除术联合门静脉-肠系膜上静脉切除及间置移植重建治疗癌症:一项荟萃分析
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