Emory Global Diabetes Research Center, Hubert Department of Global Health, Emory University, Atlanta, Georgia, USA.
J Gerontol B Psychol Sci Soc Sci. 2024 Dec 1;79(12). doi: 10.1093/geronb/gbae167.
The 50-59 age group in the United States experience higher levels of food insecurity (FI) compared to older adults. While previous research has identified an association between FI and cognition outcomes in older populations, limited research has examined midlife as a specific FI exposure window and the association of this hardship with long-run cognition outcomes.
Utilizing 14 waves of Health and Retirement Study (HRS) data (1995-2020), I applied mixed-effects models to assess the relationship between midlife FI exposure and later-life cognitive function, controlling for childhood disadvantages and other health-related and sociodemographic characteristics.
Findings indicate that both cumulative FI duration and ever experiencing FI during ages 50-59 are significantly associated with subsequent cognitive decline. Specifically, ever experiencing FI during midlife was linked to a decrease in cognitive function by 0.07 standard units (95% confidence interval [CI], -0.13 to -0.003; p < .05). In addition, each additional year of FI exposure during midlife was associated with a reduction in cognitive function by 0.01 standard units (95% CI: -0.03 to -0.003; p < .05). These associations remained robust even after accounting for a range of potential confounders and covariates.
The findings support the cumulative inequality model, suggesting that midlife FI is a significant predictor of lower cognitive function in later life. Both the timing and extent of FI during midlife are crucial factors in shaping cognitive health outcomes. Policy interventions targeting FI in the 50-59 age group could play a pivotal role in promoting healthy aging and mitigating cognitive decline in older adulthood.
与老年人相比,美国 50-59 岁年龄组经历更高水平的食物不安全(FI)。虽然先前的研究已经确定了 FI 与老年人群认知结果之间的关联,但有限的研究考察了中年作为特定的 FI 暴露窗口,以及这种困难与长期认知结果的关联。
利用健康与退休研究(HRS)的 14 个波次数据(1995-2020 年),我应用混合效应模型来评估中年 FI 暴露与晚年认知功能之间的关系,同时控制了儿童时期的劣势以及其他与健康相关和社会人口统计学特征。
研究结果表明,FI 持续时间的累积和在 50-59 岁期间经历 FI 都与随后的认知衰退显著相关。具体来说,在中年经历 FI 与认知功能下降 0.07 个标准单位相关(95%置信区间[-0.13,-0.003];p<0.05)。此外,在中年期间每增加一年的 FI 暴露与认知功能下降 0.01 个标准单位相关(95%置信区间[-0.03,-0.003];p<0.05)。即使考虑了一系列潜在的混杂因素和协变量,这些关联仍然稳健。
研究结果支持累积不平等模型,表明中年 FI 是晚年较低认知功能的重要预测因素。中年 FI 的时间和程度都是塑造认知健康结果的关键因素。针对 50-59 岁年龄组的 FI 进行政策干预,可能在促进健康老龄化和减轻老年认知衰退方面发挥关键作用。