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英国妇科癌症协会和英国更年期协会指南:妇科癌症治疗后的更年期症状管理

British Gynaecological Cancer Society and British Menopause Society guidelines: Management of menopausal symptoms following treatment of gynaecological cancer.

作者信息

Taylor Alexandra, Clement Kathryn, Hillard Timothy, Sassarini Jenifer, Ratnavelu Nithya, Baker-Rand Holly, Bowen Rebecca, Davies Melanie C, Edey Katherine, Fernandes Andreia, Ghaem-Maghami Sadaf, Gomes Nana, Gray Sarah, Hughes Eluned, Hudson Anna, Manchanda Ranjit, Manley Kristyn, Nicum Shibani, Phillips Andrew, Richardson Alison, Morrison Jo

机构信息

Department of Gynaecology Oncology, The Royal Marsden Hospital NHS Trust, London, UK.

The Institute of Cancer Research, London, UK.

出版信息

Post Reprod Health. 2024 Dec;30(4):256-279. doi: 10.1177/20533691241286666. Epub 2024 Oct 11.

Abstract

These guidelines have been developed jointly by the British Gynaecological Cancer Society and British Menopause Society to provide information for all healthcare professionals managing women treated for gynaecological cancer. Menopausal symptoms can have a significant impact on quality of life for women. Cancer therapies, including surgery, pelvic radiotherapy, chemotherapy and endocrine therapy, can all affect ovarian function. The benefits and risks of using hormone replacement therapy are considered by cancer type with guidance on the type of HRT and optimal time of commencement after cancer treatment. Vaginal estrogens can be very effective for improving urogenital symptoms and are safe for the majority of women, including those for whom systemic HRT is contraindicated with rare exceptions. Alternative options to HRT are reviewed including pharmacological and non-pharmacological approaches.

摘要

这些指南由英国妇科癌症协会和英国绝经学会联合制定,旨在为所有管理接受妇科癌症治疗女性的医疗保健专业人员提供信息。绝经症状会对女性的生活质量产生重大影响。癌症治疗,包括手术、盆腔放疗、化疗和内分泌治疗,都可能影响卵巢功能。针对不同癌症类型,会考虑使用激素替代疗法(HRT)的益处和风险,并就HRT的类型以及癌症治疗后开始使用的最佳时间提供指导。阴道雌激素对改善泌尿生殖系统症状非常有效,对大多数女性都是安全的,包括那些有罕见例外情况而禁忌全身使用HRT的女性。还会对HRT的替代选择进行综述,包括药理学和非药理学方法。

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