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侵袭性真菌性中耳炎伴周围性面瘫

Invasive fungal otitis media with peripheral facial paralysis.

作者信息

Kang Wenjie, Zhang Jie, Gao Hanbing, Guan Ming

机构信息

Department of Otolaryngology, the Fourth Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, 310006, China.

Department of Pediatrics, Hangzhou Children's Hospital, Hangzhou, 310006, China.

出版信息

Med Mycol Case Rep. 2024 Sep 27;46:100672. doi: 10.1016/j.mmcr.2024.100672. eCollection 2024 Dec.

DOI:10.1016/j.mmcr.2024.100672
PMID:39398287
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11471234/
Abstract

Invasive fungal otitis media is clinically rare and diagnosis often delayed. We report a 65-year-old female with otitis media complicated by mastoiditis and peripheral facial paralysis. Complete mastoidectomy and type II tympanoplasty, with oral administration of voriconazole for more than 3 months resulted in a successful outcome.

摘要

侵袭性真菌性中耳炎临床罕见，诊断常被延误。我们报告一例65岁女性，患有中耳炎并伴有乳突炎和周围性面瘫。行完乳突根治术及II型鼓室成形术，并口服伏立康唑3个多月，结果治疗成功。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb76/11471234/0c03214efa4d/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb76/11471234/cac88bdbfdba/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb76/11471234/c3fee7b26a5b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb76/11471234/43bddf04a289/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb76/11471234/0c03214efa4d/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb76/11471234/cac88bdbfdba/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb76/11471234/c3fee7b26a5b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb76/11471234/43bddf04a289/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb76/11471234/0c03214efa4d/gr4.jpg

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Invasive fungal otitis media with peripheral facial paralysis.侵袭性真菌性中耳炎伴周围性面瘫
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Tympanoplasty, with or without mastoidectomy, is highly effective for treatment of chronic otitis media in children.鼓膜成形术，无论是否行乳突切除术，对治疗儿童慢性中耳炎都非常有效。
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本文引用的文献

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Distribution of species and risk factors for aspergillosis in mainland China: a systematic review.中国大陆曲霉病的物种分布及危险因素：一项系统综述
Ther Adv Infect Dis. 2024 Jun 4;11:20499361241252537. doi: 10.1177/20499361241252537. eCollection 2024 Jan-Dec.
2
Invasive Fungal Otitis Media in Diabetic Patients: A Case-Based Review.糖尿病患者侵袭性真菌性中耳炎：基于病例的回顾。
J Int Adv Otol. 2023 Jan;19(1):55-60. doi: 10.5152/iao.2023.22743.
3
Single Topical Application of 1% Clotrimazole Cream in Otomycosis.1%克霉唑乳膏单次局部应用于外耳道真菌病
Indian J Otolaryngol Head Neck Surg. 2023 Apr;75(Suppl 1):147-154. doi: 10.1007/s12070-022-03206-x. Epub 2022 Dec 8.
4
Invasive Aspergillus infection of middle ear in a patient treated with secukinumab, methotrexate, and corticosteroids for psoriasis and psoriatic arthritis.治疗银屑病和银屑病关节炎患者时使用司库奇尤单抗、甲氨蝶呤和皮质类固醇，导致中耳侵袭性曲霉菌感染。
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Molecular Identification and In Vitro Antifungal Susceptibility of Aspergillus Isolates Recovered from Otomycosis Patients in Western China.从中国西部耳真菌病患者中分离出的曲霉菌的分子鉴定及体外抗真菌药敏试验。
Mycopathologia. 2020 Jun;185(3):527-535. doi: 10.1007/s11046-020-00448-7. Epub 2020 Apr 28.
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Diagnosis and treatment of otomycosis in southern China.中国南方的耳真菌病的诊断与治疗。
Mycoses. 2019 Nov;62(11):1064-1068. doi: 10.1111/myc.12979. Epub 2019 Sep 2.
7
The Molecular Identification and Antifungal Susceptibilities of Aspergillus Species Causing Otomycosis in Tochigi, Japan.日本栃木县导致外耳炎的曲霉菌属种的分子鉴定和抗真菌药敏性
Mycopathologia. 2019 Feb;184(1):13-21. doi: 10.1007/s11046-018-0299-9. Epub 2018 Oct 5.
8
Prevalence and factors predictive of intraocular fungal infection in patients with fungemia at an academic urban tertiary care center.一所城市学术型三级医疗中心真菌血症患者眼内真菌感染的患病率及预测因素
Clin Ophthalmol. 2015 Sep 29;9:1853-8. doi: 10.2147/OPTH.S91540. eCollection 2015.
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Turk J Med Sci. 2015;45(4):820-6. doi: 10.3906/sag-1407-17.
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