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一名美国公民因胃肠炎继发急性肾衰竭,经肾脏替代治疗后康复。

Acute Renal Failure Secondary to Gastroenteritis in a United States Citizen, Corrected With Renal Replacement Therapy.

作者信息

Xie Meng, Hong Angelina, Gupta Mayuri, Dragovic Dusan

机构信息

Department of Internal Medicine, HCA Florida Northwest Hospital, USA.

Department of Gastroenterology, HCA Florida Northwest Hospital, USA.

出版信息

J Community Hosp Intern Med Perspect. 2024 Sep 9;14(5):110-113. doi: 10.55729/2000-9666.1387. eCollection 2024.

DOI:10.55729/2000-9666.1387
PMID:39399201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11466333/
Abstract

Cholera is an acute gastroenteritis that can lead to fatal dehydration and metabolic derangements. Cases of cholera in the United States are typically associated with international travel. Patients who are persistently dehydrated despite aggressive rehydration and antibiotic therapy may require hemodialysis until symptom resolution and stabilization of renal function. We present a case of a 47-year-old male who recently returned from a trip to Haiti and presented with intractable abdominal pain, nausea, vomiting, and watery diarrhea. He was found to be in acute renal failure with a high anion gap metabolic acidosis of an unclear etiology. Abdominal imaging was consistent with enterocolitis, and his stool culture grew . In addition to aggressive fluid resuscitation, he underwent two intermittent hemodialysis sessions and received sodium bicarbonate and antibiotic therapy. Renal function normalized by hospital day 6. This is a novel case of severe renal failure and high anion gap metabolic acidosis in a US patient with cholera; our review of the literature did not find any case reports regarding cholera in the past decade involving a US citizen.

摘要

霍乱是一种急性肠胃炎,可导致致命的脱水和代谢紊乱。美国的霍乱病例通常与国际旅行有关。尽管进行了积极的补液和抗生素治疗,但仍持续脱水的患者可能需要进行血液透析,直到症状缓解且肾功能稳定。我们报告一例47岁男性病例,他最近从海地旅行归来,出现顽固性腹痛、恶心、呕吐和水样腹泻。他被发现患有急性肾衰竭,伴有病因不明的高阴离子间隙代谢性酸中毒。腹部影像学检查结果与小肠结肠炎相符,其粪便培养结果为……除了积极的液体复苏外,他还接受了两次间歇性血液透析治疗,并接受了碳酸氢钠和抗生素治疗。到住院第6天时,肾功能恢复正常。这是一例美国霍乱患者出现严重肾衰竭和高阴离子间隙代谢性酸中毒的新病例;我们对文献的回顾未发现过去十年中有任何关于涉及美国公民霍乱的病例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dde8/11466333/7a71c4bf5234/jchim-14-05-110f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dde8/11466333/7a71c4bf5234/jchim-14-05-110f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dde8/11466333/7a71c4bf5234/jchim-14-05-110f1.jpg

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J Community Hosp Intern Med Perspect. 2024 Sep 9;14(5):110-113. doi: 10.55729/2000-9666.1387. eCollection 2024.
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本文引用的文献

1
Acute Kidney Injury Associated With Cholera.与霍乱相关的急性肾损伤
Cureus. 2023 Jan 23;15(1):e34101. doi: 10.7759/cureus.34101. eCollection 2023 Jan.
2
Non-serogroup O1/O139 agglutinable Vibrio cholerae: a phylogenetically and genealogically neglected yet emerging potential pathogen of clinical relevance.非 O1/O139 群可凝集霍乱弧菌:一种在系统发生和系统发育上被忽视但具有临床相关性的新兴潜在病原体。
Arch Microbiol. 2022 May 14;204(6):323. doi: 10.1007/s00203-022-02866-1.
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Cholera.霍乱。
Lancet. 2022 Apr 9;399(10333):1429-1440. doi: 10.1016/S0140-6736(22)00330-0.
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Retrospective Study on Acute Kidney Injury among Cholera Patients in an Outbreak in Whitefield, Bengaluru.班加罗尔怀特菲尔德霍乱疫情中霍乱患者急性肾损伤的回顾性研究
Int J Nephrol. 2021 Jun 4;2021:6682838. doi: 10.1155/2021/6682838. eCollection 2021.
5
The Vibrio cholerae type VI secretion system: toxins, regulators and consequences.霍乱弧菌 VI 型分泌系统:毒素、调节剂及后果。
Environ Microbiol. 2020 Oct;22(10):4112-4122. doi: 10.1111/1462-2920.14976. Epub 2020 Mar 13.
6
Updated global burden of cholera in endemic countries.流行国家霍乱的全球负担最新情况。
PLoS Negl Trop Dis. 2015 Jun 4;9(6):e0003832. doi: 10.1371/journal.pntd.0003832. eCollection 2015.
7
D-lactic acidosis: an underrecognized complication of short bowel syndrome.D-乳酸酸中毒:短肠综合征一种未被充分认识的并发症。
Gastroenterol Res Pract. 2015;2015:476215. doi: 10.1155/2015/476215. Epub 2015 Apr 22.
8
Bacterial shedding in household contacts of cholera patients in Dhaka, Bangladesh.孟加拉国达卡地区霍乱患者家庭接触者中的细菌脱落情况。
Am J Trop Med Hyg. 2014 Oct;91(4):738-42. doi: 10.4269/ajtmh.14-0095. Epub 2014 Aug 11.
9
Cholera in the United States, 2001-2011: a reflection of patterns of global epidemiology and travel.美国2001 - 2011年的霍乱:全球流行病学模式与旅行情况的反映
Epidemiol Infect. 2015 Mar;143(4):695-703. doi: 10.1017/S0950268814001186. Epub 2014 May 27.
10
Massive fluid requirements and an unusual BUN/creatinine ratio for pre-renal failure in patients with cholera.霍乱患者出现大量液体需求和不常见的 BUN/肌酐比,提示为肾前性衰竭。
PLoS One. 2009 Oct 26;4(10):e7552. doi: 10.1371/journal.pone.0007552.