Nursing Department, Faculty of Health Sciences, Cukurova University, Adana, Turkey.
Brain Behav. 2024 Oct;14(10):e70091. doi: 10.1002/brb3.70091.
Multiple sclerosis (MS) is a chronic, autoimmune disease that attacks the central nervous system.
The study was conducted to determine the role of sex and other personal characteristics in the impact of symptom severity on self-care in individuals with MS.
The study was cross-sectional and was completed with 200 participants throughout Turkey. The data were collected through random and snowball sampling using the MS-related symptom checklist (MS-RS), the Fatigue Severity Scale (FSS), and the Exercise of Self-Care Agency (ESCA) form. The data obtained were analyzed using the SPSS 21. Statistical significance was evaluated at the level of p < 0.05.
The mean age of the participants was 37.97 ± 10.6 years. The mean scores were 47.4 ± 22.41 for MS-RS, 4.58 ± 2.2 for FSS, and 94.65 ± 24.76 for ESCA in females. The mean MS-RS score in males was 45 ± 25.89, FSS was 4.33 ± 2.5, and ESCA was 83.43 ± 23.95. There were no significant differences between the sexes except that the ESCA scores were higher in females (p < 0.05). According to a multiple linear regression analysis, the duration of diagnosis and sensory subdimension of MS-RS negatively affected the ESCA score in females, and this statistically significant model explained 22.6% of ESCA scores.
The study found that both sexes had clinically significant fatigue, mildly severe symptoms, and moderate self-care agency. While being a female positively affected self-care agency, disease duration, and sensory symptoms negatively affected females' self-care agency.
多发性硬化症（MS）是一种慢性自身免疫性疾病，会攻击中枢神经系统。
本研究旨在确定性别和其他个人特征在 MS 患者症状严重程度对自我护理的影响中的作用。
本研究为横断面研究，在土耳其完成了 200 名参与者。使用 MS 相关症状清单（MS-RS）、疲劳严重程度量表（FSS）和自我护理代理锻炼量表（ESCA）通过随机和滚雪球抽样收集数据。使用 SPSS 21 分析获得的数据。统计学意义评估水平为 p<0.05。
参与者的平均年龄为 37.97±10.6 岁。女性的 MS-RS 平均得分为 47.4±22.41，FSS 平均得分为 4.58±2.2，ESCA 平均得分为 94.65±24.76。男性的 MS-RS 平均得分为 45±25.89，FSS 平均得分为 4.33±2.5，ESCA 平均得分为 83.43±23.95。除了女性的 ESCA 评分较高（p<0.05）外，男女之间没有显著差异。根据多元线性回归分析，诊断持续时间和 MS-RS 的感觉子维度对女性的 ESCA 评分产生负面影响，该具有统计学意义的模型解释了 22.6%的 ESCA 评分。
本研究发现，两性均存在临床显著疲劳、轻度严重症状和中度自我护理能力。虽然女性的自我护理能力呈正相关，但疾病持续时间和感觉症状对女性的自我护理能力产生负面影响。
