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异位胰腺导致胃穿孔和弥漫性腹膜炎:一例罕见病例报告

Gastric perforation and generalized peritonitis due to heterotopic pancreas, an unusual case report.

作者信息

Gómez María N, Gómez Aurora García, Montes Irma Sánchez, Uribe Jesús Villagran, Ruiz María Fernanda Torres, Baridó Murguía María E

机构信息

Department of General Surgery, General Hospital "Dr. Miguel Silva", Morelia, Michoacán, Mexico; Street Pirul 309, Fray Antonio de San Miguel Iglesias, CP 58270 Morelia, Michoacán, Mexico.

Department of General Surgery, General Hospital "Dr. Miguel Silva", Morelia, Michoacán, Mexico.

出版信息

Int J Surg Case Rep. 2024 Nov;124:110422. doi: 10.1016/j.ijscr.2024.110422. Epub 2024 Oct 10.

DOI:10.1016/j.ijscr.2024.110422
PMID:39405755
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11525150/
Abstract

INTRODUCTION

Heterotopic pancreas is the presence of normal pancreatic tissue that is in an anatomical site different from the pancreas.

CASE REPORT

Adolescent who was admitted to the emergency room due to intense, generalized abdominal pain, which did not go away with anything, was exacerbated with movements, 24 h later vomiting that occurred as soon as he ate food was added, and severe and progressive abdominal distention, reason for admission to the service of emergencies. He had no significant family or personal medical history. On physical examination, he was found to be sick with a painful appearance, pale, sweaty, feverish, with tachycardia, he complained of intense pain, distended abdomen, with loss of hepatic dullness, with involuntary muscular resistance, with positive rebound sign, absent peristalsis. Laboratory studies were taken that reported anemia, leukocytosis and neutrophilia, blood chemistry, electrolytes, and coagulation times within normal limits; abdominal x-rays showed subdiaphragmatic free air.

DISCUSSION

The prevalence of pancreatic heterotopia in the literature varies from 0.6 % in autopsy series to 14 %, however, the increasingly frequent use of upper gastrointestinal endoscopy and endoscopic ultrasound allows early diagnosis, since whether directed or incidentally, which avoids serious complications such as gastric perforation, because it is unusual for it to occur as in this clinical case. Specifically in the stomach, involvement of the submucosa layer has been described in 73 %, muscular layer in 17 % and subserosa in 10 % of cases respectively. In cases where the disease is in an asymptomatic stage, it can be treated conservatively; it seems to be more common in men, as in our case, than in women.

CONCLUSION

In patients with chronic epigastric pain, it is essential to rule out conditions such as heterotopic pancreas, to avoid serious complications such as perforation.

摘要

引言

异位胰腺是指正常胰腺组织存在于与胰腺不同的解剖部位。

病例报告

一名青少年因剧烈的全身性腹痛被送入急诊室,腹痛持续不缓解,活动时加剧,24小时后出现进食后即刻呕吐,且伴有严重的进行性腹胀,遂因这些症状被收治入急诊。他没有显著的家族或个人病史。体格检查发现他病容痛苦,面色苍白、多汗、发热,伴有心动过速,主诉剧烈疼痛、腹部膨隆,肝浊音界消失,有不自主肌抵抗,反跳痛阳性,肠鸣音消失。实验室检查显示贫血、白细胞增多及中性粒细胞增多,血液化学、电解质及凝血时间均在正常范围内;腹部X线显示膈下游离气体。

讨论

文献中胰腺异位症的患病率在尸检系列中为0.6%至14%不等,然而,上消化道内镜检查和内镜超声检查的使用日益频繁,使得能够早期诊断,因为无论是直接发现还是偶然发现,都能避免诸如胃穿孔等严重并发症,因为像本临床病例中那样发生胃穿孔的情况并不常见。具体在胃中,分别有73%的病例描述为黏膜下层受累,17%为肌层受累,10%为浆膜下层受累。在疾病处于无症状阶段的情况下,可以进行保守治疗;与我们的病例一样,该病似乎在男性中比在女性中更常见。

结论

对于患有慢性上腹痛的患者,排除异位胰腺等疾病以避免诸如穿孔等严重并发症至关重要。

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