聚乙二醇二甲基丙烯酸酯链长对热敏性N-异丙基丙烯酰胺衍生物电导率及其他选定理化性质的影响

Influence of Poly(Ethylene Glycol) Dimethacrylates' Chain Length on Electrical Conductivity and Other Selected Physicochemical Properties of Thermally Sensitive N-isopropylacrylamide Derivatives.

作者信息

Gola Agnieszka, Podżus Borys, Gruszka Kinga, Musiał Witold

机构信息

Department of Physical Chemistry and Biophysics, Pharmaceutical Faculty, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.

出版信息

Polymers (Basel). 2024 Sep 30;16(19):2786. doi: 10.3390/polym16192786.

DOI:10.3390/polym16192786

PMID:39408495

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11478501/

Abstract

Thermosensitive polymers P1-P6 of N-isopropylacrylamide (PNIPA) and poly(ethylene glycol) dimethacrylates (PEGDMAs), av. Mn 550-20,000, were synthesized via surfactant-free precipitation polymerization (SFPP) using ammonium persulfate (APS) at 70 °C. The polymerization course was monitored by the conductivity. The hydrodynamic diameters (HDs) and the polydispersity indexes (PDIs) of the aqueous dispersion of P1-P6 in the 18-45 °C range, assessed via dynamic light scattering (DLS), were at 18° as follows (nm): 73.95 ± 19.51 (PDI 0.57 ± 0.08), 74.62 ± 0.76 (PDI 0.56 ± 0,01), 69.45 ± 1.47 (PDI 0.57 ± 0.03), 196.2 ± 2.50 (PDI 0.53 ± 0.04), 194.30 ± 3.36 (PDI 0.56 ± 0.04), 81.99 ± 0.53 (PDI 0.56 ± 0.01), 76.87 ± 0.30 (PDI 0.54 ± 0.01), respectively. The electrophoretic mobilities estimated the zeta potential (ZP) in the 18-45 °C range, and at 18 °C they were as follows (mV): -2.57 ± 0.10, -4.32 ± 0.67, -5.34 ± 0.95, --3.02 ± 0.76, -4.71 ± 2.69, -2.30 ± 0.36, -2.86 ± 0.42 for polymer dispersion P1-P6. The polymers were characterized by attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), H nuclear magnetic resonance (H NMR), thermogravimetric analysis (TG/DTA), Differential Scanning Calorimetry (DSC), and powder X-ray diffraction analysis (PXRD). The length of the cross-linker chain influences the physicochemical properties of the obtained polymers.

摘要

通过在70℃下使用过硫酸铵（APS）进行无表面活性剂沉淀聚合（SFPP），合成了平均分子量（Mn）为550 - 20,000的N - 异丙基丙烯酰胺（PNIPA）和聚（乙二醇）二甲基丙烯酸酯（PEGDMA）的热敏聚合物P1 - P6。通过电导率监测聚合过程。通过动态光散射（DLS）评估，P1 - P6水分散体在18 - 45℃范围内的流体动力学直径（HDs）和多分散指数（PDIs）在18℃时如下（nm）：73.95±19.51（PDI 0.57±0.08），74.62±0.76（PDI 0.56±0.01），69.45±1.47（PDI 0.57±0.03），196.2±2.50（PDI 0.53±0.04），194.30±3.36（PDI 0.56±0.04），81.99±0.53（PDI 0.56±0.01），76.87±0.30（PDI 0.54±0.01）。通过电泳迁移率估计18 - 45℃范围内的zeta电位（ZP），在18℃时，聚合物分散体P1 - P6的zeta电位如下（mV）：-2.57±0.10，-4.32±0.67，-5.34±0.95，-3.02±0.76，-4.71±2.69，-2.30±0.36，-2.86±0.42。通过衰减全反射傅里叶变换红外光谱（ATR - FTIR）、氢核磁共振（H NMR）、热重分析（TG / DTA）、差示扫描量热法（DSC）和粉末X射线衍射分析（PXRD）对聚合物进行了表征。交联剂链的长度影响所得聚合物的物理化学性质。