Divisão de Endocrinologia Programa de Pós-graduação em Ciências da Saúde Universidade Federal de Sergipe AracajuSE Brasil Divisão de Endocrinologia, Programa de Pós-graduação em Ciências da Saúde, Universidade Federal de Sergipe, Aracaju, SE, Brasil.
Department of Psychiatry and Psychotherapy University Hospital Hamburg-Eppendorf Hamburg Germany Department of Psychiatry and Psychotherapy, University Hospital Hamburg-Eppendorf, Hamburg, Germany and Department of Psychiatry and Psychotherapy, Technical University of Munich, Munich, Germany.
Arch Endocrinol Metab. 2024 Aug 13;68:e230265. doi: 10.20945/2359-4292-2023-0265. eCollection 2024.
Individuals with congenital isolated growth hormone deficiency (IGHD) in Northeastern Brazil have a normal lifespan with a prolonged healthspan. We hypothesize that their increased healthspan is accompanied by a reduced cognitive decline during aging. We have recently shown that these individuals have a similar total cognitive function and better attention and executive function than controls. These data were obtained using a Portuguese version of the Literacy Independent Cognitive Assessment (LICA) instrument, whose translation to facilitate cognitive research in Portuguese-speaking countries is described here.
In the first stage, a psychologist and a psychiatrist translated the LICA instrument from English into Portuguese, and an English teacher proofread the translation. The second stage included its synthesis and cultural adaptation, carried out by Brazilian authors, and changes in some words and images. The third stage involved an evaluation round with two referees (independent psychologists). The fourth stage involved a back translation of the instrument, which demonstrated > 95% agreement with the original version. The fifth stage included a study to verify the understanding of the questionnaire by responders. In the sixth stage, an endocrinologist and a psychiatrist approved the final Portuguese version of the instrument, which was then administered to 15 individuals with IGHD and 15 controls older than 50 years.
The LICA instrument was applied 59 times (5 times in the pilot study, 24 in the variability studies, and 30 in the experimental step). The interobserver and intraobserver variabilities were 99% and 96%, respectively. Cronbach's alpha was 0.76, indicating good reliability. The mean (± standard deviation) duration of the application was 39 ± 8.6 and 48.5 ± 5.8 minutes in literate and illiterate individuals, respectively.
The Portuguese version of the LICA instrument was valuable for the cognitive assessment of individuals with Itabaianinha syndrome.
巴西东北部患有先天性孤立性生长激素缺乏症(IGHD)的个体具有正常的寿命和延长的健康寿命。我们假设他们的健康寿命延长伴随着衰老过程中认知能力下降的减少。我们最近表明,这些个体的总认知功能相似,注意力和执行功能更好。这些数据是使用葡萄牙语版的Literacy Independent Cognitive Assessment(LICA)工具获得的,本文介绍了将其翻译为便于葡萄牙语国家进行认知研究的方法。
在第一阶段,一位心理学家和一位精神科医生将 LICA 工具从英语翻译成葡萄牙语,一位英语教师对翻译进行了校对。第二阶段包括由巴西作者进行的综合和文化适应,以及对一些单词和图像的修改。第三阶段涉及两位评审员(独立心理学家)的评估回合。第四阶段涉及对工具的回译,结果显示与原始版本的一致性 >95%。第五阶段包括一项研究,以验证应答者对问卷的理解。第六阶段,内分泌学家和精神科医生批准了该工具的最终葡萄牙语版本,然后对 15 名 IGHD 患者和 15 名年龄大于 50 岁的对照者进行了测试。
LICA 工具共应用了 59 次(试点研究 5 次,变异性研究 24 次,实验步骤 30 次)。观察者间和观察者内的变异性分别为 99%和 96%。Cronbach's alpha 为 0.76,表明可靠性良好。有读写能力和无读写能力个体的应用平均(±标准差)持续时间分别为 39 ± 8.6 分钟和 48.5 ± 5.8 分钟。
LICA 工具的葡萄牙语版本对 Itabaianinha 综合征个体的认知评估很有价值。