伴有眼部受累的颞动脉炎的治疗。

Treatment of temporal arteritis with ocular involvement.

作者信息

Rosenfeld S I, Kosmorsky G S, Klingele T G, Burde R M, Cohn E M

出版信息

Am J Med. 1986 Jan;80(1):143-5. doi: 10.1016/0002-9343(86)90066-5.

Abstract

A 78-year-old white woman had catastrophic visual loss in one eye due to temporal arteritis. Despite treatment with doses of oral corticosteroids high enough to normalize the Westergren erythrocyte sedimentation rate, she experienced progressive retinal ischemia with visual loss in the second eye. The use of 1,000 mg of pulsed intravenous methylprednisolone every 12 hours restored her vision. Brief hospitalization of patients with arteritic ischemic optic neuropathy for treatment with intravenous methylprednisolone may offer a significant chance of visual recovery of the involved eye and provide optimal protection to the uninvolved eye.

摘要

一名78岁的白人女性因颞动脉炎导致一只眼睛出现灾难性视力丧失。尽管使用了剂量足以使魏氏血沉率恢复正常的口服皮质类固醇进行治疗，但她仍出现了进行性视网膜缺血，另一只眼睛也出现了视力丧失。每12小时静脉注射1000毫克脉冲式甲基强的松龙使她的视力得以恢复。动脉炎性缺血性视神经病变患者短期住院接受静脉注射甲基强的松龙治疗，可能为患眼提供显著的视力恢复机会，并为未受累眼提供最佳保护。