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2019冠状病毒病对厄瓜多尔血脂异常患病率的影响:一项2017年至2022年的横断面研究。

Impact of COVID-19 on the prevalence of dyslipidemia in Ecuador: A cross-sectional study between 2017 and 2022.

作者信息

Rivadeneira Josue, Fuenmayor-González Luis, Jácome-García Michelle, Flores-Lastra Nancy, Delgado Hugo, Otzen Tamara

机构信息

Universidad de La Frontera, Doctorado en Ciencias Médicas, Temuco, Chile; Zero Biomedical Research, Quito, Ecuador; Núcleo Milenio de Sociomedicina, Santiago, Chile.

Zero Biomedical Research, Quito, Ecuador; Universidad Central del Ecuador, Facultad de Ciencias Médicas, Quito, Ecuador.

出版信息

Aten Primaria. 2025 Apr;57(4):103007. doi: 10.1016/j.aprim.2024.103007. Epub 2024 Oct 18.

Abstract

OBJECTIVE

To determine changes in the prevalence of dyslipidemias during the pre-COVID-19 and COVID-19 years in three regions of Ecuador.

DESIGN

Cross-sectional study. SITE: Quito, Guayaquil, and El Coca.

PARTICIPANTS

Adults with cholesterol, HDL, LDL, and triglyceride levels at primary care centers from January 2017 to December 2022.

INTERVENTIONS

Not applicable.

MAIN MEASUREMENTS

Data were obtained from five BIODIMED primary care centers. Cholesterol, HDL, LDL, and triglyceride levels were classified according to the ATP III guidelines. Dyslipidemia was considered present when one or more parameters exceeded specific thresholds. Sociodemographic variables and the year of examination were included as independent variables.

RESULTS

The study analyzed 110,521 participants' laboratory results, where 65.3% were males and an average age of 38±12 years. The study spanned the Andean (72.4%), Coast (15.4%), and Amazonic region (12.3%). Pre-pandemic exams constituted 60.9% of the sample. The prevalence of dyslipidemia increased gradually from 43.1% in 2017 to 64.1% in 2022. Cholesterol levels, HDL, and LDL exhibited changes during the pandemic, with an increased risk of hypercholesterolemia, low HDL, and high LDL.

CONCLUSIONS

During the COVID-19 pandemic, a notable increase in the prevalence of dyslipidemias, including hypercholesterolemia, high triglycerides, and high LDL, was determined across three regions in Ecuador.

摘要

目的

确定厄瓜多尔三个地区在新冠疫情前及疫情期间血脂异常患病率的变化。

设计

横断面研究。

地点

基多、瓜亚基尔和埃尔科卡。

参与者

2017年1月至2022年12月在初级保健中心进行胆固醇、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)和甘油三酯水平检测的成年人。

干预措施

不适用。

主要测量指标

数据来自五个BIODIMED初级保健中心。胆固醇、HDL、LDL和甘油三酯水平根据ATP III指南进行分类。当一个或多个参数超过特定阈值时,即认为存在血脂异常。社会人口统计学变量和检查年份作为自变量。

结果

该研究分析了110,521名参与者的实验室结果,其中65.3%为男性,平均年龄为38±12岁。该研究涵盖安第斯地区(72.4%)、海岸地区(15.4%)和亚马逊地区(12.3%)。疫情前的检查占样本的60.9%。血脂异常的患病率从2017年的43.1%逐渐上升至2022年的64.1%。在疫情期间,胆固醇水平、HDL和LDL出现了变化,高胆固醇血症、低HDL和高LDL的风险增加。

结论

在新冠疫情期间,厄瓜多尔三个地区血脂异常的患病率显著增加,包括高胆固醇血症、高甘油三酯和高LDL。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1473/11533009/f9f295b51e1f/gr1.jpg

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