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综述:与海洋无脊椎动物相关细菌产生的抗菌化合物

Mini review: antimicrobial compounds produced by bacteria associated with marine invertebrates.

作者信息

Amran Ramzi H, Jamal Mamdoh T, Bowrji Saba, Sayegh Fotoon, Santanumurti Muhammad Browijoyo, Satheesh Sathianeson

机构信息

Department of Marine Biology, Faculty of Marine Sciences, King Abdulaziz University, P.O. Box 80207, 21589, Jeddah, Saudi Arabia.

Department of Marine Biology and Fisheries, Faculty of Marine Science and Environments, Hodeidah University, P.O. Box 3114, Hodeidah, Yemen.

出版信息

Folia Microbiol (Praha). 2025 Apr;70(2):271-292. doi: 10.1007/s12223-024-01209-5. Epub 2024 Oct 24.

Abstract

The marine environment is considered one of the most important ecosystems with high biodiversity. Microorganisms in this environment are variable and coexist with other marine organisms. The microbes associated with other marine organisms produce compounds with biological activity that may help the host's defense against invading organisms. The symbiotic association of bacteria with marine invertebrates is of ecological and biotechnological importance. Biologically active metabolites isolated from bacteria associated with marine invertebrates are considered potential sources of natural antimicrobial molecules for treating infectious diseases. Many studies have been conducted to screen the antimicrobial activity of metabolites produced by bacteria associated with marine invertebrates. This work provides an overview of the advancements in antimicrobial compound research on bacteria associated with marine invertebrates.

摘要

海洋环境被认为是生物多样性高的最重要生态系统之一。该环境中的微生物种类多样,与其他海洋生物共存。与其他海洋生物相关联的微生物会产生具有生物活性的化合物,这些化合物可能有助于宿主抵御入侵生物。细菌与海洋无脊椎动物的共生关系具有生态和生物技术意义。从与海洋无脊椎动物相关联的细菌中分离出的具有生物活性的代谢产物被认为是治疗传染病的天然抗菌分子的潜在来源。已经开展了许多研究来筛选与海洋无脊椎动物相关联的细菌所产生代谢产物的抗菌活性。这项工作概述了与海洋无脊椎动物相关联的细菌抗菌化合物研究的进展。

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