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痘苗病毒天坛株晚期11000道尔顿多肽及其5'侧翼区的编码基因:核苷酸序列

Gene coding for the late 11,000-dalton polypeptide of the Tian Tan strain of vaccinia virus and its 5'-flanking region: nucleotide sequence.

作者信息

Tsao H, Ren G F, Chu C M

出版信息

J Virol. 1986 Feb;57(2):693-6. doi: 10.1128/JVI.57.2.693-696.1986.

Abstract

A late gene coding for a major structural polypeptide of 11,000 daltons from the Tian Tan strain of vaccinia virus was cloned. A comparison of the sequences from Tian Tan and WR strains of vaccinia virus revealed that there were differences in four nucleotides and one amino acid and that there was little homology between the 5'-flanking sequences of the late and the early genes. However, substantial homology was detected between the 5'-flanking sequences of the late genes.

摘要

克隆了来自天坛株痘苗病毒的一个编码11000道尔顿主要结构多肽的晚期基因。对天坛株和WR株痘苗病毒的序列比较显示,在四个核苷酸和一个氨基酸上存在差异,并且晚期基因和早期基因的5'侧翼序列之间几乎没有同源性。然而,在晚期基因的5'侧翼序列之间检测到了显著的同源性。

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