从一名健康中国女性供体建立诱导多能干细胞系（SDPHi006-A）是一项成就。
Establishing an induced pluripotent stem cell line (SDPHi006-A) from a healthy Chinese female donor represents an accomplishment.
作者信息
Shao Jing, Shao Chunhong, Yang Guang, Jin Yan
机构信息
Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China.
Department of General Surgery, The 960th Hospital of the PLA Joint Logistics Support Force, Jinan, Shandong 250031, China.
出版信息
Stem Cell Res. 2024 Dec;81:103590. doi: 10.1016/j.scr.2024.103590. Epub 2024 Oct 20.
We isolated peripheral blood mononuclear cells (PBMCs) from a healthy female donor, and successfully converted into induced pluripotent stem cells (iPSCs) by using non-integrating episomal vectors. These iPSCs displayed a normal karyotype, expressed markers of pluripotency, and showed the capacity to differentiate into three germ layers in vitro, which could be utilized for future research endeavors.
我们从一名健康女性供体中分离出外周血单个核细胞（PBMCs），并通过使用非整合型附加体载体成功将其转化为诱导多能干细胞（iPSCs）。这些iPSCs显示出正常的核型，表达多能性标志物，并在体外表现出分化为三个胚层的能力，可用于未来的研究工作。
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