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2型糖尿病患者的抑郁与生活质量

Depression and quality of life in patients with type 2 diabetes mellitus.

作者信息

Bayani Mohammad Ali, Shakiba Nava, Bijani Ali, Moudi Sussan

机构信息

Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

School of Medicine, Babol University of Medical Sciences, Babol, Iran.

出版信息

Caspian J Intern Med. 2022 Spring;13(2):335-342. doi: 10.22088/cjim.13.2.3.

Abstract

BACKGROUND

Depression as a frequent comorbidity in patients with diabetes requires serious attention, as failure to early detect and treat it can adversely affect the patients' complications This study was performed to assess the prevalence of depression and quality of life in these patients.

METHODS

This cross-sectional study was carried-out on adult patients with type 2 diabetes mellitus referred to the endocrinology hospital clinics affiliated to Babol University of Medical Sciences, Babol, Iran, during 2018-2019. The presence and severity of depressive symptoms in patients have been assessed by Beck Depression Inventory-II; and the quality of life was measured by SF-36 questionnaire.

RESULTS

Totally, 400 patients with type 2 diabetes mellitus (300 females and 100 males) with mean age of 55.36±11.56 years were recruited. One hundred and thirty (32.5%) had depressive symptoms. Of the patients with depression, 115 (28.8%) had mild and 15 (3.8%) had moderate depression. After entering different variables in logistic regression analysis, gender (P=0.036) and ophthalmic complications (P=0.011) showed a significant association with depressive symptoms. The patients with depression had a worse quality of life compared to those who had not depressive symptoms. Quality of life score in patients with depression was significantly lower than patients without depression (p<0.0001).

CONCLUSION

Nearly one third of the patients with type II diabetes mellitus might have depression. Diabetic patients with depression have a worse quality of life compared to those who have not depression symptoms.

摘要

背景

抑郁症作为糖尿病患者常见的合并症,需要引起高度重视,因为未能早期发现和治疗会对患者的并发症产生不利影响。本研究旨在评估这些患者中抑郁症的患病率和生活质量。

方法

本横断面研究于2018 - 2019年对转诊至伊朗巴博尔医科大学附属内分泌医院门诊的成年2型糖尿病患者进行。采用贝克抑郁量表第二版评估患者抑郁症状的存在及严重程度;采用SF - 36问卷测量生活质量。

结果

共纳入400例2型糖尿病患者(300例女性,100例男性),平均年龄55.36±11.56岁。130例(32.5%)有抑郁症状。在有抑郁症状的患者中,115例(28.8%)为轻度抑郁,15例(3.8%)为中度抑郁。在逻辑回归分析中纳入不同变量后,性别(P = 0.036)和眼部并发症(P = 0.011)与抑郁症状有显著关联。与无抑郁症状的患者相比,有抑郁症状的患者生活质量更差。抑郁患者的生活质量得分显著低于无抑郁患者(p < 0.0001)。

结论

近三分之一的2型糖尿病患者可能患有抑郁症。与无抑郁症状的糖尿病患者相比,有抑郁症状的糖尿病患者生活质量更差。

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