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优化呼吸机相关性肺炎的诊断与管理:气管内导管生物膜检测方法及细菌定植的系统评价

Optimizing Diagnosis and Management of Ventilator-Associated Pneumonia: A Systematic Evaluation of Biofilm Detection Methods and Bacterial Colonization on Endotracheal Tubes.

作者信息

Codru Ioana Roxana, Vintilă Bogdan Ioan, Sava Mihai, Bereanu Alina Simona, Neamțu Sandra Ioana, Bădilă Raluca Maria, Bîrluțiu Victoria

机构信息

Faculty of Medicine, Lucian Blaga University of Sibiu,550169 Sibiu, Romania.

County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.

出版信息

Microorganisms. 2024 Sep 28;12(10):1966. doi: 10.3390/microorganisms12101966.

DOI:10.3390/microorganisms12101966
PMID:39458275
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11509713/
Abstract

Healthcare-associated infections, such as ventilator-associated pneumonia and biofilm formation on intubation cannulas, impose significant burdens on hospitals, affecting staffing, finances, and patient wellbeing, while also increasing the risk of patient mortality. We propose a research study aimed at exploring various methodologies for detecting these infections, discovered in the biofilm on medical devices, particularly tracheal cannulas, and understanding the role of each method in comprehending these infections from an etiological perspective. Our investigation also involves an analysis of the types of endotracheal tubes utilized in each case, the bacteria species identified, and strategies for combating biofilm-associated infections. The potential impact of our research is the substantial improvement of patient care through enhanced diagnosis and management of these infections.

摘要

医疗保健相关感染,如呼吸机相关性肺炎和插管上的生物膜形成,给医院带来了巨大负担,影响人员配备、财务状况和患者健康,同时还增加了患者死亡风险。我们提出一项研究,旨在探索检测这些在医疗器械(特别是气管插管)生物膜中发现的感染的各种方法,并从病因学角度理解每种方法在认识这些感染方面的作用。我们的调查还包括分析每种情况下使用的气管导管类型、鉴定出的细菌种类以及对抗生物膜相关感染的策略。我们研究的潜在影响是通过加强对这些感染的诊断和管理,大幅改善患者护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7fb/11509713/bc157102d524/microorganisms-12-01966-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7fb/11509713/48e23336554a/microorganisms-12-01966-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7fb/11509713/db14e8630d48/microorganisms-12-01966-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7fb/11509713/3bde6f117d1e/microorganisms-12-01966-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7fb/11509713/f4432c76251a/microorganisms-12-01966-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7fb/11509713/bc157102d524/microorganisms-12-01966-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7fb/11509713/48e23336554a/microorganisms-12-01966-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7fb/11509713/db14e8630d48/microorganisms-12-01966-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7fb/11509713/3bde6f117d1e/microorganisms-12-01966-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7fb/11509713/f4432c76251a/microorganisms-12-01966-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7fb/11509713/bc157102d524/microorganisms-12-01966-g005.jpg

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