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Proc IEEE Inst Electr Electron Eng. 2021 May;109(5):820-838. doi: 10.1109/JPROC.2021.3054390. Epub 2021 Feb 26.
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Algorithmic fairness in artificial intelligence for medicine and healthcare.人工智能在医学和医疗保健中的算法公平性。
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Multimodal Data Matters: Language Model Pre-Training Over Structured and Unstructured Electronic Health Records.多模态数据至关重要:基于结构化和非结构化电子健康记录的语言模型预训练
IEEE J Biomed Health Inform. 2023 Jan;27(1):504-514. doi: 10.1109/JBHI.2022.3217810. Epub 2023 Jan 4.
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Virtual Biopsy by Using Artificial Intelligence-based Multimodal Modeling of Binational Mammography Data.基于人工智能的中德两国乳腺 X 线摄影数据的多模态建模的虚拟活检。
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8
Integrated multimodal artificial intelligence framework for healthcare applications.用于医疗保健应用的集成多模态人工智能框架。
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Prediction of Postoperative Deterioration in Cardiac Surgery Patients Using Electronic Health Record and Physiologic Waveform Data.基于电子健康记录和生理波形数据预测心脏手术患者术后恶化情况。
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Multimodal deep learning for Alzheimer's disease dementia assessment.多模态深度学习在阿尔茨海默病痴呆评估中的应用。
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基于深度学习的电子健康记录多模态数据融合研究进展

[Research progress on electronic health records multimodal data fusion based on deep learning].

作者信息

Fan Yong, Zhang Zhengbo, Wang Jing

机构信息

Medical Innovation Research Department, Chinese PLA General Hospital, Beijing 100853, P. R. China.

School of Computer and Information Technology, Beijing Jiaotong University, Beijing 100044, P. R. China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2024 Oct 25;41(5):1062-1071. doi: 10.7507/1001-5515.202310011.

DOI:10.7507/1001-5515.202310011
PMID:39462676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11527755/
Abstract

Currently, the development of deep learning-based multimodal learning is advancing rapidly, and is widely used in the field of artificial intelligence-generated content, such as image-text conversion and image-text generation. Electronic health records are digital information such as numbers, charts, and texts generated by medical staff using information systems in the process of medical activities. The multimodal fusion method of electronic health records based on deep learning can assist medical staff in the medical field to comprehensively analyze a large number of medical multimodal data generated in the process of diagnosis and treatment, thereby achieving accurate diagnosis and timely intervention for patients. In this article, we firstly introduce the methods and development trends of deep learning-based multimodal data fusion. Secondly, we summarize and compare the fusion of structured electronic medical records with other medical data such as images and texts, focusing on the clinical application types, sample sizes, and the fusion methods involved in the research. Through the analysis and summary of the literature, the deep learning methods for fusion of different medical modal data are as follows: first, selecting the appropriate pre-trained model according to the data modality for feature representation and post-fusion, and secondly, fusing based on the attention mechanism. Lastly, the difficulties encountered in multimodal medical data fusion and its developmental directions, including modeling methods, evaluation and application of models, are discussed. Through this review article, we expect to provide reference information for the establishment of models that can comprehensively utilize various modal medical data.

摘要

目前,基于深度学习的多模态学习发展迅速,并广泛应用于人工智能生成内容领域,如图像-文本转换和图像-文本生成。电子健康记录是医务人员在医疗活动过程中使用信息系统生成的数字信息,如数字、图表和文本。基于深度学习的电子健康记录多模态融合方法可以辅助医疗领域的医务人员全面分析诊疗过程中产生的大量医疗多模态数据,从而实现对患者的准确诊断和及时干预。在本文中,我们首先介绍基于深度学习的多模态数据融合方法和发展趋势。其次,我们总结并比较结构化电子病历与图像和文本等其他医疗数据的融合,重点关注临床应用类型、样本量以及研究所涉及的融合方法。通过对文献的分析和总结,不同医疗模态数据融合的深度学习方法如下:一是根据数据模态选择合适的预训练模型进行特征表示和后期融合,二是基于注意力机制进行融合。最后,讨论了多模态医疗数据融合中遇到的困难及其发展方向,包括建模方法、模型评估和应用。通过这篇综述文章,我们期望为建立能够综合利用各种模态医疗数据的模型提供参考信息。