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Predictive modeling of biomedical temporal data in healthcare applications: review and future directions.

作者信息

Patharkar Abhidnya, Cai Fulin, Al-Hindawi Firas, Wu Teresa

机构信息

School of Computing and Augmented Intelligence, Arizona State University, Tempe, AZ, United States.

ASU-Mayo Center for Innovative Imaging, Arizona State University, Tempe, AZ, United States.

出版信息

Front Physiol. 2024 Oct 15;15:1386760. doi: 10.3389/fphys.2024.1386760. eCollection 2024.


DOI:10.3389/fphys.2024.1386760
PMID:39473609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11519529/
Abstract

Predictive modeling of clinical time series data is challenging due to various factors. One such difficulty is the existence of missing values, which leads to irregular data. Another challenge is capturing correlations across multiple dimensions in order to achieve accurate predictions. Additionally, it is essential to take into account the temporal structure, which includes both short-term and long-term recurrent patterns, to gain a comprehensive understanding of disease progression and to make accurate predictions for personalized healthcare. In critical situations, models that can make multi-step ahead predictions are essential for early detection. This review emphasizes the need for forecasting models that can effectively address the aforementioned challenges. The selection of models must also take into account the data-related constraints during the modeling process. Time series models can be divided into statistical, machine learning, and deep learning models. This review concentrates on the main models within these categories, discussing their capability to tackle the mentioned challenges. Furthermore, this paper provides a brief overview of a technique aimed at mitigating the limitations of a specific model to enhance its suitability for clinical prediction. It also explores ensemble forecasting methods designed to merge the strengths of various models while reducing their respective weaknesses, and finally discusses hierarchical models. Apart from the technical details provided in this document, there are certain aspects in predictive modeling research that have arisen as possible obstacles in implementing models using biomedical data. These obstacles are discussed leading to the future prospects of model building with artificial intelligence in healthcare domain.

摘要

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本文引用的文献

[1]
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