Department of Ophthalmology, Children's Hospital of Fudan University, The National Children's Medical Center, 399 Wanyuan Road, Shanghai, 201102, China.
Biomed Eng Online. 2024 Nov 4;23(1):110. doi: 10.1186/s12938-024-01300-5.
The purpose of this study was to evaluate the repeatability and agreement of multispectral refraction topography (MRT) in measuring retinal refraction before and after cycloplegia in children. The results of this study will provide valuable insights into the accuracy and reliability of MRT as a tool for assessing retinal refraction in pediatric patients.
Children aged 7 to 18 years old were recruited for this prospective research. The central and peripheral retinal refraction was measured three times using multispectral refraction topography (MRT) before and after cycloplegia. The retinal deviation value (RDV) was used to describe the average peripheral refractive error of the retina. In addition, objective refraction (OR) and subjective refraction (SR) measurements were also performed.
A total of 60 children with a mean age of 10.50 ± 1.81 years were enrolled. Before cycloplegia, all the central and peripheral retinal refraction parameters showed good repeatability with the lowest intraclass correlation coefficient (ICC) being 0.78 in the retinal deviation value from 45° eccentricity to 53° of the retina (RDV 45-53). After cycloplegia, the repeatability of MRT was significantly enhanced (lowest ICC = 0.91 in RDV-I). The 95% limits of agreement (LoA) of the central refraction and OR ranged from - 2.1 to 1.8 D before cycloplegia, and from - 1.69 to 0.27 D after cycloplegia. The 95% LoA of the central refraction and SR ranged from - 1.57 to 0.36 D after cycloplegia. All the 95% LoA demonstrated high agreement.
The MRT shows high agreement with autorefractometry and experienced optometrist in measuring central refraction. Additionally, the MRT provides good repeatable measurements of retinal peripheral refraction before and after cycloplegia in schoolchildren.
本研究旨在评估多光谱折射地形图（MRT）在睫状肌麻痹前后测量儿童视网膜屈光度的重复性和一致性。本研究的结果将为 MRT 作为评估儿科患者视网膜屈光度的工具的准确性和可靠性提供有价值的见解。
本前瞻性研究招募了 7 至 18 岁的儿童。使用多光谱折射地形图（MRT）在睫状肌麻痹前后三次测量中央和周边视网膜屈光度。视网膜偏离值（RDV）用于描述视网膜周边平均屈光误差。此外，还进行了客观折射（OR）和主观折射（SR）测量。
共纳入 60 名平均年龄为 10.50±1.81 岁的儿童。睫状肌麻痹前，所有中央和周边视网膜屈光度参数的重复性均较好，最低的组内相关系数（ICC）为视网膜 45°至 53°偏心处的视网膜偏离值（RDV 45-53）为 0.78。睫状肌麻痹后，MRT 的重复性显著增强（RDV-I 的最低 ICC 为 0.91）。中央屈光度和 OR 的 95%一致性界限（LoA）在睫状肌麻痹前为-2.1 至 1.8 D，在睫状肌麻痹后为-1.69 至 0.27 D。中央屈光度和 SR 的 95% LoA 在睫状肌麻痹后为-1.57 至 0.36 D。所有 95% LoA 均显示高度一致性。
MRT 在测量中央屈光度方面与自动折射计和经验丰富的验光师具有高度一致性。此外，MRT 可在睫状肌麻痹前后对学龄儿童的视网膜周边屈光度进行良好的可重复性测量。
