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基于虚拟现实的康复对中风患者心理健康和生活质量的影响:随机对照试验的系统评价和荟萃分析

Effect of Virtual Reality-Based Rehabilitation on Mental Health and Quality of Life of Stroke Patients: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

作者信息

Wang Saikun, Meng Hongli, Zhang Yong, Mao Jing, Zhang Changyue, Qian Chunting, Ma Yueping, Guo Lirong

机构信息

Department of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin, China.

Department of Forensic Medicine, School of Basic Medical Sciences, Jilin University, Changchun, Jilin, China.

出版信息

Arch Phys Med Rehabil. 2025 Apr;106(4):607-617. doi: 10.1016/j.apmr.2024.10.006. Epub 2024 Nov 2.

DOI:10.1016/j.apmr.2024.10.006
PMID:39491576
Abstract

OBJECTIVES

To conduct a meta-analysis to investigate the effect of virtual reality (VR)-based rehabilitation on the mental health and quality of life of stroke patients.

DATA SOURCES

The search strategy was conducted in 5 databases (PubMed, Scopus, Web of Science, Embase, and Cochrane Library databases) from inception to December 2023.

STUDY SELECTION

Randomized controlled trials (RCTs) comparing the effectiveness of standard rehabilitation and VR-based rehabilitation for stroke patients.

DATA EXTRACTION

Data from the included articles were extracted independently by 2 authors, with any disagreements resolved through consultation with a third author. The extracted data included the first author's name, country/region, publication year, sample size, mean/median age of participants, sex distribution (the proportion of males), VR type, duration of rehabilitation, comparison, intervention, and assessment of outcome.

DATA SYNTHESIS

A total of 29 studies involving 1561 stroke patients were included. The results showed that compared with standard rehabilitation, VR-based rehabilitation remarkably reduced anxiety symptoms [SMD=-0.97 (95% CI [-1.84, -0.09], P<.0001)], depression symptoms [SMD=-0.94 (95% CI [-1.46, -0.42], P<.001)], and improved quality of life [SMD=0.94 (95% CI [0.42, 1.45], P<.001)] of stroke patients. Subgroup analysis showed that immersive VR was particularly effective in reducing anxiety and depression symptoms compared to nonimmersive VR. The longer the duration of VR intervention, exceeding 6 weeks, the more significant the effect of improving anxiety and depression symptoms. Meanwhile, VR-based rehabilitation significantly improved the psychological state and quality of life of European patients.

CONCLUSIONS

VR-based rehabilitation significantly reduces anxiety and depression symptoms and enhances the quality of life in stroke patients compared to standard rehabilitation. The most notable improvements were observed with immersive VR-based rehabilitation programs over 6 weeks in duration, particularly among European patients.

摘要

目的

进行一项荟萃分析,以研究基于虚拟现实(VR)的康复对中风患者心理健康和生活质量的影响。

数据来源

检索策略在5个数据库(PubMed、Scopus、Web of Science、Embase和Cochrane图书馆数据库)中从建库至2023年12月进行。

研究选择

比较标准康复与基于VR的康复对中风患者有效性的随机对照试验(RCT)。

数据提取

纳入文章的数据由2名作者独立提取,如有分歧通过与第三位作者协商解决。提取的数据包括第一作者姓名、国家/地区、出版年份、样本量、参与者的平均/中位年龄、性别分布(男性比例)、VR类型、康复持续时间、比较、干预和结果评估。

数据合成

共纳入29项研究,涉及1561名中风患者。结果表明,与标准康复相比,基于VR的康复显著减轻了焦虑症状[标准化均数差(SMD)=-0.97(95%置信区间[-1.84,-0.09],P<0.0001)]、抑郁症状[SMD=-0.94(95%置信区间[-1.46,-0.42],P<0.001)],并改善了中风患者的生活质量[SMD=0.94(95%置信区间[0.42,1.45],P<0.001)]。亚组分析表明,与非沉浸式VR相比,沉浸式VR在减轻焦虑和抑郁症状方面特别有效。VR干预持续时间越长,超过6周,改善焦虑和抑郁症状的效果越显著。同时,基于VR的康复显著改善了欧洲患者的心理状态和生活质量。

结论

与标准康复相比,基于VR的康复显著减轻了中风患者的焦虑和抑郁症状,并提高了生活质量。在持续时间超过6周的沉浸式VR康复计划中观察到最显著的改善,特别是在欧洲患者中。

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