Department of Biochemistry, H. N. B. Garhwal University, Srinagar Garhwal, India.
Department of Pharmaceutical Chemistry, H. N. B. Garhwal University, Srinagar Garhwal, India.
Phytother Res. 2020 Oct;34(10):2518-2533. doi: 10.1002/ptr.6702. Epub 2020 Apr 20.
Fruits of Terminalia chebula Retz. (Combretaceae) are widely used as crude drugs in various traditional medicine systems. The aim of this article is to review the available scientific information regarding the traditional uses, bioactive chemical constituents and the pharmacological activities of T. chebula. Numerous researches conducted on T. chebula have confirmed the presence of wide range of the phytochemicals such as flavonoids, tannins, phenolic acids and other bioactive compounds. T. chebula is also widely studied regarding its pharmacological activities such as antioxidant, hepatoprotective, neuroprotective, cytotoxic, antidiabetic, anti-inflammatory activities among others. However, more in vivo and clinical studies for mechanism-based pharmacological evaluation should be conducted in future to provide stronger scientific evidences for their traditional uses.
使君子科诃子（Terminalia chebula Retz.）的果实被广泛用作各种传统医学体系中的粗药。本文旨在综述诃子的传统用途、生物活性化学成分和药理学活性的现有科学信息。对诃子进行的大量研究证实，其含有广泛的植物化学物质，如类黄酮、单宁、酚酸和其他生物活性化合物。诃子的药理学活性也得到了广泛研究，如抗氧化、保肝、神经保护、细胞毒性、抗糖尿病、抗炎等。然而，未来应该进行更多基于机制的体内和临床药理学评价研究，为其传统用途提供更强有力的科学证据。
