Lal Mohan, Sutradhar Dipankar
School of Advanced Science and Languages, VIT Bhopal University, Madhya Pradesh, India.
Nat Prod Res. 2024 Nov 5:1-7. doi: 10.1080/14786419.2024.2424390.
L., a medicinal plant rich in secondary metabolites, was studied for optimising bioactive compound extraction from various parts of the plant using ethanol-water (50:50), ethanol, and methanol solvents. Analysis of extracts for key phytochemicals like polyphenols, flavonoids, saponins, and alkaloids was performed using HPTLC, HPLC and gas chromatography. The ethanol-water mixture proved best for extracting saponins and polyphenols, ethanol for flavonoids, and methanol for alkaloids. The fruit yielded the highest saponin content (59.34% ± 3.87), while leaves were richest in polyphenols (18.94% ± 1.39), flavonoids (5.15% ± 1.01), and alkaloids (26.46% ± 1.71). Leaf extracts showed the highest antibacterial activity against and , and stem extracts were effective against . Root, stem, and leaf extracts exhibited antifungal activity with leaf extract also demonstrating strong phytoestrogenic activity. These findings highlight the varied phytochemical profiles and biological activities of , suggesting their potential therapeutic uses.
L.是一种富含次生代谢产物的药用植物，研究人员使用乙醇-水（50:50）、乙醇和甲醇溶剂，对从该植物各个部位提取生物活性化合物的方法进行了优化。使用高效薄层色谱法（HPTLC）、高效液相色谱法（HPLC）和气相色谱法对提取物中的关键植物化学物质（如多酚、黄酮类化合物、皂苷和生物碱）进行了分析。结果表明，乙醇-水混合物最适合提取皂苷和多酚，乙醇最适合提取黄酮类化合物，甲醇最适合提取生物碱。果实中的皂苷含量最高（59.34% ± 3.87），而叶片中多酚（18.94% ± 1.39）、黄酮类化合物（5.15% ± 1.01）和生物碱（26.46% ± 1.71）的含量最为丰富。叶片提取物对[具体菌种1]和[具体菌种2]表现出最高的抗菌活性，茎提取物对[具体菌种3]有效。根、茎和叶提取物均具有抗真菌活性，叶提取物还表现出较强的植物雌激素活性。这些发现突出了L.植物多样的植物化学特征和生物活性，表明了它们潜在的治疗用途。
