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利用深度堆叠集成技术优化 MRI 图像上膝骨关节炎严重程度的预测。

Optimizing knee osteoarthritis severity prediction on MRI images using deep stacking ensemble technique.

机构信息

Department of Computer Science & Engineering, School of Computer Science & Engineering, Manipal University Jaipur, Jaipur, Rajasthan, India.

Department of Artificial Intelligence & Machine Learning, Computer Science & Engineering, Manipal University Jaipur, Jaipur, Rajasthan, India.

出版信息

Sci Rep. 2024 Nov 5;14(1):26835. doi: 10.1038/s41598-024-78203-x.

DOI:10.1038/s41598-024-78203-x
PMID:39500982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11538306/
Abstract

Knee osteoarthritis (KOA) represents a well-documented degenerative arthropathy prevalent among the elderly population. KOA is a persistent condition, also referred to as progressive joint Disease, stemming from the continual deterioration of cartilage. Predominantly afflicting individuals aged 45 and above, this ailment is commonly labeled as a "wear and tear" joint disorder, targeting joints such as the knee, hand, hips, and spine. Osteoarthritis symptoms typically increase gradually, contributing to the deterioration of articular cartilage. Prominent indicators encompass pain, stiffness, tenderness, swelling, and the development of bone spurs. Diagnosis typically involves the utilization of Radiographic X-ray images, Magnetic Resonance Imaging (MRI), and Computed Tomography (CT) Scan by medical professionals and experts. However, this conventional approach is time-consuming, and also sometimes tedious for medical professionals. In order to address the limitation of time and expedite the diagnostic process, deep learning algorithms have been implemented in the medical field. In the present investigation, four pre-trained models, specifically CNN, AlexNet, ResNet34 and ResNet-50, were utilized to predict the severity of KOA. Further, a Deep stack ensemble technique was employed to achieve optimal performance resulting to the accuracy of 99.71%.

摘要

膝骨关节炎(KOA)是一种常见于老年人群的有充分文献记载的退行性关节病。KOA 是一种持续性疾病,也称为进行性关节疾病,源于软骨的持续恶化。主要影响 45 岁及以上的人群,这种疾病通常被称为“磨损”关节疾病,主要影响膝盖、手、臀部和脊柱等关节。骨关节炎症状通常逐渐加重,导致关节软骨恶化。突出的指标包括疼痛、僵硬、压痛、肿胀和骨刺的形成。诊断通常包括医疗专业人员和专家使用 X 射线图像、磁共振成像(MRI)和计算机断层扫描(CT)扫描。然而,这种传统方法既耗时,对医疗专业人员来说也有时很繁琐。为了解决时间限制的问题并加快诊断过程,深度学习算法已经在医学领域得到了应用。在本研究中,使用了四个预训练模型,即 CNN、AlexNet、ResNet34 和 ResNet-50,来预测 KOA 的严重程度。此外,还采用了深度堆叠集成技术以获得最佳性能,准确率达到 99.71%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ec/11538306/91779810f286/41598_2024_78203_Fig11_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ec/11538306/91779810f286/41598_2024_78203_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ec/11538306/fef3203d8afa/41598_2024_78203_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ec/11538306/6efb9eec419b/41598_2024_78203_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ec/11538306/565cf995059d/41598_2024_78203_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ec/11538306/aafc5bff1040/41598_2024_78203_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ec/11538306/655d882555b0/41598_2024_78203_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ec/11538306/d5c437a99b44/41598_2024_78203_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ec/11538306/7384ebe21cb0/41598_2024_78203_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ec/11538306/91779810f286/41598_2024_78203_Fig11_HTML.jpg

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