Sagar K B, Wann L S, Paulsen W H, Romhilt D W
J Am Coll Cardiol. 1986 Mar;7(3):681-7. doi: 10.1016/s0735-1097(86)80480-6.
Doppler echocardiographic characteristics of normally functioning Hancock and Björk-Shiley prostheses in the mitral and aortic positions were studied in 50 patients whose valvular function was considered normal by clinical evaluation. Doppler studies were also performed in 46 patients with suspected malfunction of Hancock and Björk-Shiley valves and who subsequently underwent cardiac catheterization. Mean gradients were estimated for both mitral and aortic valve prostheses and valve area was calculated for the mitral prostheses. Doppler prosthetic mitral valve gradient and valve area showed good correlation with values obtained with cardiac catheterization (r = 0.93 and 0.97, respectively) for both types of prosthetic valves. The correlation coefficient (r = 0.93) for mean prosthetic aortic valve gradient was also good, although Doppler echocardiography overestimated the mean gradient at lower degrees of obstruction. Regurgitation of Hancock and Björk-Shiley prostheses in the mitral and aortic positions was correctly diagnosed. These results suggest that Doppler echocardiography is a reliable method for the characterization of normal and abnormal prosthetic valve function.
对50例经临床评估瓣膜功能正常的患者，研究了二尖瓣和主动脉瓣位置正常工作的汉考克（Hancock）和比约克-希利（Björk-Shiley）人工瓣膜的多普勒超声心动图特征。还对46例疑似汉考克和比约克-希利瓣膜功能异常且随后接受心导管检查的患者进行了多普勒研究。估算了二尖瓣和主动脉瓣人工瓣膜的平均压差，并计算了二尖瓣人工瓣膜的瓣口面积。对于两种类型的人工瓣膜，多普勒人工二尖瓣压差和瓣口面积与心导管检查获得的值均显示出良好的相关性（分别为r = 0.93和0.97）。人工主动脉瓣平均压差的相关系数（r = 0.93）也较好，尽管在梗阻程度较低时，多普勒超声心动图高估了平均压差。二尖瓣和主动脉瓣位置的汉考克和比约克-希利人工瓣膜的反流得到了正确诊断。这些结果表明，多普勒超声心动图是一种用于描述正常和异常人工瓣膜功能的可靠方法。
