• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Trace elements in the spinal cord and other tissues in motor neuron disease.运动神经元病中脊髓及其他组织中的微量元素
J Neurol Neurosurg Psychiatry. 1986 Feb;49(2):211-5. doi: 10.1136/jnnp.49.2.211.
2
Manganese, selenium and other trace elements in spinal cord, liver and bone in motor neurone disease.运动神经元病患者脊髓、肝脏和骨骼中的锰、硒及其他微量元素。
Eur Neurol. 1991;31(1):7-11. doi: 10.1159/000116626.
3
Free amino acid concentrations in spinal tissue from patients dying of motor neuron disease.死于运动神经元疾病患者脊髓组织中的游离氨基酸浓度。
Acta Neurol Scand. 1982 Nov;66(5):594-9. doi: 10.1111/j.1600-0404.1982.tb03148.x.
4
Neutron activation analysis of trace elements in motor neuron disease spinal cord.
Neurodegeneration. 1995 Dec;4(4):383-90. doi: 10.1006/neur.1995.0046.
5
Spinal cord metabolic changes in murine retrovirus-induced motor neuron disease.小鼠逆转录病毒诱导的运动神经元疾病中的脊髓代谢变化。
Brain Res Bull. 1983 Dec;11(6):681-6. doi: 10.1016/0361-9230(83)90011-4.
6
Neuronal RNA in motor neuron disease.运动神经元病中的神经元RNA
Adv Neurol. 1982;36:89-103.
7
Metals in spinal cord tissue of patients dying of motor neuron disease.
Ann Neurol. 1979 Jul;6(1):21-4. doi: 10.1002/ana.410060105.
8
Trace element studies in amyotrophic lateral sclerosis (ALS).肌萎缩侧索硬化症（ALS）中的微量元素研究
Acta Pharmacol Toxicol (Copenh). 1986;59 Suppl 7:454-7. doi: 10.1111/j.1600-0773.1986.tb02801.x.
9
[Content of zinc, copper, iron, manganese and calcium in bone and liver of rats during zinc depletion and repletion].
Zentralbl Veterinarmed A. 1977 Mar;24(3):177-88.
10
Ubiquitin gene expression in brain and spinal cord in motor neurone disease.运动神经元病中脑和脊髓的泛素基因表达
Neurosci Lett. 1989 Jul 31;102(2-3):343-8. doi: 10.1016/0304-3940(89)90103-1.

引用本文的文献

1
The position of geochemical variables as causal co-factors of diseases of unknown aetiology.地球化学变量作为病因不明疾病的因果辅助因素的地位。
SN Appl Sci. 2022;4(8):236. doi: 10.1007/s42452-022-05113-w. Epub 2022 Jul 27.
2
A perspective on persistent toxicants in veterans and amyotrophic lateral sclerosis: identifying exposures determining higher ALS risk.老兵与肌萎缩性侧索硬化症中持久性毒物的研究视角：确定导致更高 ALS 风险的暴露因素。
J Neurol. 2022 May;269(5):2359-2377. doi: 10.1007/s00415-021-10928-5. Epub 2022 Jan 1.
3
Implementation of X-ray fluorescence microscopy for investigation of elemental abnormalities in amyotrophic lateral sclerosis.实施X射线荧光显微镜术以研究肌萎缩侧索硬化症中的元素异常。
Neurochem Res. 2006 Mar;31(3):321-31. doi: 10.1007/s11064-005-9030-6. Epub 2006 May 3.
4
Determination of selenium in the human brain by graphite furnace atomic absorption spectrometry.石墨炉原子吸收光谱法测定人脑中的硒
Biol Trace Elem Res. 1996 Jul;54(1):9-21. doi: 10.1007/BF02785316.
5
Indices of free radical activity in the cerebrospinal fluid in motor neuron disease.运动神经元病患者脑脊液中自由基活性指标
J Neurol Neurosurg Psychiatry. 1987 Jul;50(7):919-22. doi: 10.1136/jnnp.50.7.919.

本文引用的文献

1
RESPONSE TO TREATMENT WITH CHELATING AGENTS OF ANAEMIA, CHRONIC ENCEPHALOPATHY, AND MYELOPATHY DUE TO LEAD POISONING.铅中毒所致贫血、慢性脑病和脊髓病的螯合剂治疗反应
J Neurol Neurosurg Psychiatry. 1964 Dec;27(6):536-41. doi: 10.1136/jnnp.27.6.536.
2
Mercury intoxication simulating amyotrophic lateral sclerosis.模拟肌萎缩侧索硬化症的汞中毒
JAMA. 1983 Aug 5;250(5):642-3.
3
Increased manganese level in spinal cords of amyotrophic lateral sclerosis determined by radiochemical neutron activation analysis.通过放射化学中子活化分析测定肌萎缩侧索硬化症患者脊髓中锰含量升高。
J Neurol Sci. 1983 Oct;61(2):283-93. doi: 10.1016/0022-510x(83)90012-6.
4
Trace elements in cerebrospinal fluid in motor neurone disease.运动神经元病患者脑脊液中的微量元素
Br Med J (Clin Res Ed). 1984 Jun 16;288(6433):1791-2. doi: 10.1136/bmj.288.6433.1791.
5
A new hypothesis of the etiology of amyotrophic lateral sclerosis. The DNA hypothesis.肌萎缩侧索硬化症病因的新假说。DNA假说。
Arch Neurol. 1982 Nov;39(11):677-80. doi: 10.1001/archneur.1982.00510230003001.
6
Base composition of RNA obtained from motor neurons in amyotrophic lateral sclerosis.从肌萎缩侧索硬化症运动神经元中获取的RNA的碱基组成。
J Neuropathol Exp Neurol. 1981 Mar;40(2):193-8. doi: 10.1097/00005072-198103000-00010.
7
RNA content and volume of motor neurons in amyotrophic lateral sclerosis. II. The lumbar intumescence and nucleus dorsalis.
J Neuropathol Exp Neurol. 1981 Mar;40(2):187-92. doi: 10.1097/00005072-198103000-00009.
8
Chronic lead intoxication mimicking motor neurone disease.酷似运动神经元病的慢性铅中毒
Br Med J. 1968 Nov 9;4(5627):387-8. doi: 10.1136/bmj.4.5627.387-d.
9
Motor neurone disease and exposure to lead.运动神经元病与铅暴露
J Neurol Neurosurg Psychiatry. 1970 Dec;33(6):877-85. doi: 10.1136/jnnp.33.6.877.
10
Lead content of neuromuscular tissue in amyotrophic lateral sclerosis: case report and other considerations.肌萎缩侧索硬化症中神经肌肉组织的铅含量：病例报告及其他考量
Br J Ind Med. 1974 Oct;31(4):275-87. doi: 10.1136/oem.31.4.275.

运动神经元病中脊髓及其他组织中的微量元素

Trace elements in the spinal cord and other tissues in motor neuron disease.

作者信息

Mitchell J D, East B W, Harris I A, Prescott R J, Pentland B

出版信息

J Neurol Neurosurg Psychiatry. 1986 Feb;49(2):211-5. doi: 10.1136/jnnp.49.2.211.

DOI:10.1136/jnnp.49.2.211
PMID:3950642
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1028692/
Abstract

Trace elements were estimated in the spinal cord, liver and bone of five patients dying of motor neuron disease and five control subjects dying of non-neurological disease. The content of selenium in cord and liver and the cord manganese level were significantly increased in the motor neuron disease patients. These findings are discussed in terms of the possible aetiology of motor neuron disease.

摘要

对五名死于运动神经元病的患者以及五名死于非神经系统疾病的对照受试者的脊髓、肝脏和骨骼中的微量元素进行了评估。运动神经元病患者脊髓和肝脏中的硒含量以及脊髓中的锰含量显著升高。根据运动神经元病可能的病因对这些发现进行了讨论。