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运动神经元病中脊髓及其他组织中的微量元素

Trace elements in the spinal cord and other tissues in motor neuron disease.

作者信息

Mitchell J D, East B W, Harris I A, Prescott R J, Pentland B

出版信息

J Neurol Neurosurg Psychiatry. 1986 Feb;49(2):211-5. doi: 10.1136/jnnp.49.2.211.

Abstract

Trace elements were estimated in the spinal cord, liver and bone of five patients dying of motor neuron disease and five control subjects dying of non-neurological disease. The content of selenium in cord and liver and the cord manganese level were significantly increased in the motor neuron disease patients. These findings are discussed in terms of the possible aetiology of motor neuron disease.

摘要

对五名死于运动神经元病的患者以及五名死于非神经系统疾病的对照受试者的脊髓、肝脏和骨骼中的微量元素进行了评估。运动神经元病患者脊髓和肝脏中的硒含量以及脊髓中的锰含量显著升高。根据运动神经元病可能的病因对这些发现进行了讨论。

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本文引用的文献

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Trace elements in cerebrospinal fluid in motor neurone disease.运动神经元病患者脑脊液中的微量元素
Br Med J (Clin Res Ed). 1984 Jun 16;288(6433):1791-2. doi: 10.1136/bmj.288.6433.1791.
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RNA content and volume of motor neurons in amyotrophic lateral sclerosis. II. The lumbar intumescence and nucleus dorsalis.
J Neuropathol Exp Neurol. 1981 Mar;40(2):187-92. doi: 10.1097/00005072-198103000-00009.
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Motor neurone disease and exposure to lead.运动神经元病与铅暴露
J Neurol Neurosurg Psychiatry. 1970 Dec;33(6):877-85. doi: 10.1136/jnnp.33.6.877.

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