亚马逊地区一种莫巴病毒（汉坦病毒科）的首次描述。

First description of a mobatvirus (Hantaviridae) in the Amazon region.

作者信息

Hernández Leonardo Henrique Almeida, da Paz Thito Yan Bezerra, da Silva Sandro Patroca, de Barros Bruno de Cássio Veloso, Coelho Taciana Fernandes Sousa Barbosa, Cruz Ana Cecília Ribeiro

机构信息

Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ministry of Health, Ananindeua, PA, Brazil; Virology Graduate Program, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ministry of Health, Ananindeua, PA, Brazil.

Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ministry of Health, Ananindeua, PA, Brazil.

出版信息

Virus Res. 2024 Dec;350:199494. doi: 10.1016/j.virusres.2024.199494. Epub 2024 Nov 13.

DOI:10.1016/j.virusres.2024.199494

PMID:39521252

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11605466/

Abstract

From 1988-2023, Pará accounted for the highest proportion of deforestation among all states in the Brazilian Amazon. Specifically, 57.20 % of the territory in the Santa Bárbara municipality was deforested as of 2023. Since 2017, the Hantaviridae family has included viruses identified in nonrodent vertebrates, such as mobatviruses (from moles and bats). In the current metagenomic analysis of a pool of multiple organs of a Carollia brevicauda bat, we obtained sequences for three segments of the previously described Buritiense virus (BURV); to date, only the L segment had been sequenced for this mobatvirus. This study provides the first description of BURV in the Amazon region and provides information on the S and M segments of the virus. These findings corroborate the presence of BURV in Brazil in an area far from the site of the first detection and in another bat species.

摘要

1988年至2023年期间，帕拉州在巴西亚马逊地区所有州中森林砍伐比例最高。具体而言，截至2023年，圣巴巴拉市57.20%的领土被砍伐。自2017年以来，汉坦病毒科包括在非啮齿动物脊椎动物中发现的病毒，如莫巴病毒（来自鼹鼠和蝙蝠）。在当前对短尾叶口蝠多个器官样本的宏基因组分析中，我们获得了先前描述的布里蒂恩斯病毒（BURV）三个片段的序列；迄今为止，该莫巴病毒仅L片段有测序记录。本研究首次描述了亚马逊地区的布里蒂恩斯病毒，并提供了该病毒S和M片段的信息。这些发现证实了布里蒂恩斯病毒在巴西一个远离首次发现地点的地区以及另一种蝙蝠物种中的存在。