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糖尿病儿童和青少年的家庭血糖监测。一项为期3年的可行性研究。

Home blood glucose monitoring in diabetic children and adolescents. A 3-year feasibility study.

作者信息

Hermansson G, Ludvigsson J, Larsson Y

出版信息

Acta Paediatr Scand. 1986 Jan;75(1):98-105. doi: 10.1111/j.1651-2227.1986.tb10164.x.

DOI:10.1111/j.1651-2227.1986.tb10164.x
PMID:3953282
Abstract

In order to elucidate the question whether blood glucose monitoring should replace glucosuria testing in childhood diabetes 160 diabetic children and adolescents were invited to participate in a feasibility study on home blood glucose testing. Seventeen girls and 15 boys with an age of 4-21 years and duration of diabetes for 0.3-18.7 years accepted, thus a selection of motivated patients. They performed 20-22 diurnal blood glucose profiles, each consisting of 7 blood samples, during a 3 month period. Thereafter, all patients were encouraged to continue blood glucose self-control and the actual performance of the 32 patients was evaluated 3 years later. Daily glucosuria tests were also made and HbA1 was analysed. Patients' attitudes were evaluated through 2 questionnaires. The study shows that blood glucose monitoring is feasible in the actual age groups. Most patients were positive towards blood tests, particularly because it gave an immediate answer to an actual problem, but its introduction did not change the metabolic control. However, pain restricted its daily use and only 6.4% of the patients preferred blood testing to urinalysis for long term use. Furthermore, the correlation between home glucosuria and HbA1 was as good as between home blood glucose and HbA1. It is concluded, that blood glucose self-monitoring is a valuable tool in the management of childhood diabetes, but that it should be regarded as a complement to and not a substitute for daily home urinalysis.

摘要

为了阐明儿童糖尿病患者的血糖监测是否应取代尿糖检测这一问题,160名糖尿病儿童和青少年被邀请参与一项家庭血糖检测的可行性研究。17名女孩和15名男孩,年龄在4至21岁之间,糖尿病病程为0.3至18.7年,接受了邀请,因此这是一组积极性较高的患者。他们在3个月的时间里进行了20至22次日间血糖监测,每次监测由7份血样组成。此后,鼓励所有患者继续进行血糖自我监测,并在3年后评估了32名患者的实际执行情况。同时也进行了每日尿糖检测,并分析了糖化血红蛋白(HbA1)。通过两份问卷评估了患者的态度。研究表明,血糖监测在实际年龄组中是可行的。大多数患者对血液检测持积极态度,特别是因为它能立即回答实际问题,但引入血糖监测并未改变代谢控制情况。然而,疼痛限制了其日常使用,只有6.4%的患者长期更喜欢血液检测而非尿液分析。此外,家庭尿糖与糖化血红蛋白(HbA1)之间的相关性与家庭血糖和糖化血红蛋白(HbA1)之间的相关性一样好。得出的结论是,血糖自我监测是儿童糖尿病管理中的一项有价值的工具,但应将其视为日常家庭尿液分析的补充,而非替代。

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Home blood glucose monitoring in diabetic children and adolescents. A 3-year feasibility study.糖尿病儿童和青少年的家庭血糖监测。一项为期3年的可行性研究。
Acta Paediatr Scand. 1986 Jan;75(1):98-105. doi: 10.1111/j.1651-2227.1986.tb10164.x.
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引用本文的文献

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Do high blood glucose peaks contribute to higher HbA1c? Results from repeated continuous glucose measurements in children.高血糖峰值会导致更高的糖化血红蛋白(HbA1c)吗?来自儿童重复连续血糖测量的结果。
World J Pediatr. 2008 Aug;4(3):215-21. doi: 10.1007/s12519-008-0040-8.
2
Glucose monitoring as a guide to diabetes management. Critical subject review.血糖监测作为糖尿病管理的指南。关键主题综述。
Can Fam Physician. 1996 Jun;42:1142-6, 1149-52.
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The relationship of blood glucose and haemoglobin A1 levels in diabetic subjects.糖尿病患者血糖与糖化血红蛋白水平的关系。
Ir J Med Sci. 1994 May;163(5):233-5. doi: 10.1007/BF02943257.