Delage G, Montplaisir S, Rémy-Prince S, Pierri E
CMAJ. 1986 Apr 15;134(8):897-901.
From January 1982 to June 1984, 30,315 serum specimens from pregnant women at nine hospitals in the Montreal area were screened for hepatitis B surface antigen (HBsAg). Of the specimens 103, from 98 women, were positive, a prevalence rate of 3.4 per 1000. The ethnic origin of the 98 women and the number who were also positive for e antigen (HBeAg) were as follows: French-Canadian, 29 (3 HBeAg-positive); Asian, 28 (14); Haitian, 32 (0); other, 7 (0); and unknown, 2 (0). The prevalence rates of HBsAg positivity according to ethnic origin at one of the hospitals were 73.9 in Asians, 33.1 in Haitians, 0.9 in French Canadians and 8.0 in women of other extraction. If the prevalence rate found in this study is true for the 95 000 live births that occur yearly in the province of Quebec, there are an estimated 323 infants at risk for hepatitis B virus (HBV) infection each year in the province. Screening programs for detecting HBV carriage in pregnant women should be instituted, since recent studies have shown combined active-passive immunization to be effective in preventing perinatal transmission of HBV infection.
1982年1月至1984年6月，对蒙特利尔地区9家医院的30315份孕妇血清样本进行了乙肝表面抗原（HBsAg）筛查。其中103份样本（来自98名女性）呈阳性，患病率为千分之3.4。这98名女性的种族来源以及e抗原（HBeAg）也呈阳性的人数如下：法裔加拿大人，29名（3名HBeAg阳性）；亚洲人，28名（14名）；海地人，32名（0名）；其他，7名（0名）；不明，2名（0名）。其中一家医院按种族来源划分的HBsAg阳性患病率分别为：亚洲人73.9‰，海地人33.1‰，法裔加拿大人0.9‰，其他族裔女性8.0‰。如果本研究中发现的患病率适用于魁北克省每年发生的95000例活产，那么该省每年估计有323名婴儿有感染乙肝病毒（HBV）的风险。鉴于最近的研究表明，联合主动-被动免疫在预防HBV感染的围产期传播方面是有效的，因此应开展筛查项目以检测孕妇中的HBV携带者。
