Amaro-Gahete Francisco J, De-la-O Alejandro, Jurado-Fasoli Lucas, Sanchez-Delgado Guillermo, Ruiz Jonatan R, Castillo Manuel J
EFFECTS-262 Research Group, Department of Medical Physiology, School of Medicine, University of Granada, Spain; PROmoting FITness and Health Through Physical Activity Research Group (PROFITH), Sport and Health University Research Institute (iMUDS), Department of Physical Education and Sports, Faculty of Sport Sciences, University of Granada, Spain.
EFFECTS-262 Research Group, Department of Medical Physiology, School of Medicine, University of Granada, Spain.
Clin Nutr. 2020 Nov;39(11):3230-3240. doi: 10.1016/j.clnu.2020.02.001. Epub 2020 Feb 8.
BACKGROUND & AIMS: This study compares the influence of different exercise training programs on basal metabolic rate (BMR) and fat oxidation, in basal conditions (BFox) and during exercise (MFO), in sedentary, middle-aged adults.
The study subjects of this 12 week-long, randomised controlled trial, were 71 middle-aged adults (age 53.5 ± 4.9 years; 52% women). Subjects were randomly assigned to one of the following groups: (1) no exercise, (2) concurrent training based on international physical activity recommendations (PAR group), (3) high intensity interval training (HIIT group), and (4) high intensity interval training plus whole-body electromyostimulation (HIIT + EMS group). Subject BMR, BFox and MFO were determined by indirect calorimetry before and after the intervention.
The HIIT + EMS subjects showed significant increases in BFox following the intervention compared with the control group (all P = 0.043); no such differences were seen in the PAR and HIIT compared with the control group (all P ≥ 0.1). A significant increase in post-intervention MFO was noted for the HIIT and HIIT + EMS group compared to the non-exercise control group (P < 0.05); no such difference was seen in the PAR group compared to the control group (all P ≥ 0.05).
Twelve weeks of high intensity interval training plus whole-body electromyostimulation may increase the BFox and MFO of middle-aged sedentary adults. These findings have important clinical implications; a well-designed high-intensity interval training program plus whole-body electromyostimulation might be followed to help combat the appearance of chronic metabolic diseases characterized by metabolic inflexibility in middle-aged sedentary adults, though it will be necessary to determine how long the effects last.
本研究比较了不同运动训练方案对久坐不动的中年成年人基础状态（基础脂肪氧化，BFox）和运动期间（运动中脂肪氧化，MFO）的基础代谢率（BMR）和脂肪氧化的影响。
在这项为期12周的随机对照试验中，研究对象为71名中年成年人（年龄53.5±4.9岁；52%为女性）。受试者被随机分配到以下组之一：（1）不运动，（2）基于国际身体活动建议的联合训练（PAR组），（3）高强度间歇训练（HIIT组），以及（4）高强度间歇训练加全身肌电刺激（HIIT + EMS组）。干预前后通过间接测热法测定受试者的BMR、BFox和MFO。
与对照组相比，HIIT + EMS组受试者干预后BFox显著增加（所有P = 0.043）；与对照组相比，PAR组和HIIT组未见此类差异（所有P≥0.1）。与不运动的对照组相比，HIIT组和HIIT + EMS组干预后MFO显著增加（P < 0.05）；与对照组相比，PAR组未见此类差异（所有P≥0.05）。
为期12周的高强度间歇训练加全身肌电刺激可能会增加久坐不动的中年成年人的BFox和MFO。这些发现具有重要的临床意义；可能需要遵循精心设计的高强度间歇训练方案加全身肌电刺激，以帮助对抗以中年久坐不动成年人代谢不灵活为特征的慢性代谢疾病的出现，不过有必要确定这些效果能持续多久。
