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用于评估颈动脉内膜切除术围手术期轻微并发症的E-PASS评分的有效性

Validity of E-PASS Score for Evaluating Perioperative Minor Complications Associated with Carotid Endarterectomy.

作者信息

Morishima Yutaka, Kawabori Masahito, Ito Yoichi M, Gekka Masayuki, Furukawa Koji, Niiya Yoshimasa, Fujimura Miki

机构信息

Department of Neurosurgery, Graduate School of Medicine, Hokkaido University.

Department of Neurosurgery, Otaru General Hospital.

出版信息

Neurol Med Chir (Tokyo). 2025 Jan 15;65(1):9-14. doi: 10.2176/jns-nmc.2024-0035. Epub 2024 Nov 25.

Abstract

Carotid endarterectomy (CEA) is conducted to reduce the risk of cerebral infarction; therefore, a low complication rate is highly required. To predict long-term morbidity and mortality, various scoring systems have been considered; nonetheless, a model that can be utilized to estimate nonmajor temporary complications and minor complications is currently lacking. To evaluate the occurrence rate of perioperative complications in various surgical domains, the E-PASS (Estimation of Physiological Ability and Surgical Stress) score is employed. This study was carried out to investigate the utility of the E-PASS score as a predictive factor for the risk of minor complications in patients undergoing CEA. The retrospective analysis was performed for 104 consecutive series of CEA procedures carried out at Otaru Municipal Hospital. The correlation between E-PASS and the rate of minor complications was examined. Sensitivity and specificity were used to construct a receiver operating characteristic curve, and the area under the curve (AUC) was calculated for accuracy. Postoperative minor complications occurred in eight cases (7.7%), including six vagal nerve injuries and two pneumonia cases. Three categorical data-preoperative risk score, surgical stress scores, and comprehensive risk score (CRS) -showed a good relationship with the postoperative minor complication. Among them, CRS presented the highest sensitivity and specificity, as indicated by an AUC of 0.68. The CRS cutoff value was calculated as -0.068, with a 1.7% postoperative minor complication rate for those lower than -0.068 and 14.0% for those higher than -0.068. The E-PASS score was effective for evaluating and predicting postoperative minor complications in patients with CEA procedures.

摘要

颈动脉内膜切除术(CEA)旨在降低脑梗死风险;因此,对低并发症发生率有很高要求。为预测长期发病率和死亡率,人们考虑了各种评分系统;然而,目前缺乏一种可用于估计非重大临时并发症和轻微并发症的模型。为评估不同手术领域围手术期并发症的发生率,采用了E-PASS(生理能力和手术应激评估)评分。本研究旨在探讨E-PASS评分作为CEA患者轻微并发症风险预测因素的效用。对小樽市立医院连续进行的104例CEA手术系列进行回顾性分析。检查了E-PASS与轻微并发症发生率之间的相关性。使用敏感性和特异性构建受试者工作特征曲线,并计算曲线下面积(AUC)以评估准确性。术后有8例(7.7%)发生轻微并发症,包括6例迷走神经损伤和2例肺炎。术前风险评分、手术应激评分和综合风险评分(CRS)这三个分类数据与术后轻微并发症有良好关系。其中,CRS的敏感性和特异性最高,AUC为0.68。CRS临界值计算为-0.068,低于-0.068者术后轻微并发症发生率为1.7%,高于-0.068者为14.0%。E-PASS评分对评估和预测接受CEA手术患者的术后轻微并发症有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e1d/11807687/f1be77702c36/1349-8029-65-0009-g001.jpg

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