Esteban A, Molina-Negro P
J Neurol Neurosurg Psychiatry. 1986 Jan;49(1):58-63. doi: 10.1136/jnnp.49.1.58.
A series of 53 cases of primary hemifacial spasm have been evaluated by means of blink reflexes and their results compared with a normal control group. Reflex responses were obtained by percutaneous electrical stimulus of both the supraorbital nerve (trigemino-facial reflex), and the facial nerve at the stylo-mastoid region (facio-facial reflex). The R2 response was considered abnormal when its latency was shortened (hyperactivity) or delayed (hypoactivity). Thirty-six out of 53 cases with primary hemifacial spasm showed abnormal responses, with a combination of facial nerve impairment (delayed R2 in the facio-facial reflex) and trigeminal-facial hyperactivity (shortened R2 in the trigemino-facial reflex). Five cases showed hyperactivity in both the trigemino-facial reflex and the facio-facial reflex reflexes. These results suggest a state of hyperexcitability, probably at the level of the facial nucleus, combined with a peripheral facial nerve involvement in a high proportion of patients with primary hemifacial spasm.
通过眨眼反射对53例原发性面肌痉挛患者进行了评估，并将结果与正常对照组进行了比较。通过经皮电刺激眶上神经（三叉神经 - 面部反射）和茎乳突区的面神经（面 - 面反射）获得反射反应。当R2反应的潜伏期缩短（活动亢进）或延迟（活动减退）时，认为其异常。53例原发性面肌痉挛患者中有36例显示异常反应，表现为面神经损害（面 - 面反射中R2延迟）和三叉神经 - 面部活动亢进（三叉神经 - 面部反射中R2缩短）。5例患者的三叉神经 - 面部反射和面 - 面反射均表现为活动亢进。这些结果表明，在原发性面肌痉挛患者中，很大一部分可能在面神经核水平存在过度兴奋状态，并伴有周围面神经受累。
