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腹腔镜再次手术治疗术后诊断的胆囊癌:胆囊管处理的技术选择

Laparoscopic Reoperation for Postoperatively Diagnosed Gallbladder Cancer: Technical Options for Cystic Duct Management.

作者信息

Park Yeshong, Kim Jinju, Kang MeeYoung, Lee Boram, Lee Hae Won, Cho Jai Young, Han Ho-Seong, Yoon Yoo-Seok

机构信息

Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Korea.

出版信息

Ann Surg Oncol. 2025 Mar;32(3):1817-1818. doi: 10.1245/s10434-024-16552-7. Epub 2024 Nov 27.

DOI:10.1245/s10434-024-16552-7
PMID:39601938
Abstract

BACKGROUND

Gallbladder cancer is a rare disease with poor prognosis, for which surgical resection is considered the only curative treatment. The widespread adoption of laparoscopic cholecystectomy for benign biliary diseases has led to an increased incidence of postoperatively diagnosed gallbladder cancer. Several studies have proposed that tumors exceeding stage T2 require additional resection. However, reoperation for postoperatively diagnosed gallbladder cancer is technically difficult due to inflammatory adhesion or fibrosis around the hepatoduodenal ligament and gallbladder bed. For such reasons, there are limited evidence regarding the safety and feasibility of laparoscopic reoperation and no clear indications for when to perform minimally invasive surgery.

METHODS

In this multimedia article, we present the laparoscopic reoperation techniques for postoperatively diagnosed gallbladder cancer. We focus specifically on various approaches to surgically manage the cystic duct stump, depending on the length of remnant stump, degree of surrounding fibrosis, and margin status.

RESULTS

We represent three cases with different approaches. In the first case, a patient with a long remnant stump is managed with clip ligation and resection of the stump. Second, a patient with a short remnant stump and severe fibrosis is treated with stump excision and suture closure. Lastly, bile duct resection is performed for a patient with margin involvement during the initial operation.

CONCLUSIONS

Various technical options exist to approach the remnant cystic duct stump during laparoscopic reoperation for postoperatively diagnosed gallbladder cancer.

摘要

背景

胆囊癌是一种预后较差的罕见疾病,手术切除被认为是唯一的治愈性治疗方法。腹腔镜胆囊切除术在良性胆道疾病中的广泛应用导致术后诊断胆囊癌的发病率增加。多项研究提出,超过T2期的肿瘤需要额外切除。然而,由于肝十二指肠韧带和胆囊床周围的炎症粘连或纤维化,术后诊断胆囊癌的再次手术在技术上具有挑战性。因此,关于腹腔镜再次手术的安全性和可行性的证据有限,且对于何时进行微创手术没有明确的指征。

方法

在这篇多媒体文章中,我们介绍了术后诊断胆囊癌的腹腔镜再次手术技术。我们特别关注根据残余残端长度、周围纤维化程度和切缘情况,对胆囊管残端进行手术处理的各种方法。

结果

我们展示了三例采用不同方法的病例。第一例,残端较长的患者采用钛夹结扎和残端切除进行处理。第二例,残端较短且纤维化严重的患者采用残端切除和缝合关闭进行治疗。最后,对初次手术时切缘受累的患者进行胆管切除。

结论

在术后诊断胆囊癌的腹腔镜再次手术中,存在多种处理残余胆囊管残端的技术选择。

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The optimal extent of surgery in T2 gallbladder cancer and the need for hepatectomy: A meta-analysis.T2期胆囊癌手术的最佳范围及肝切除术的必要性:一项荟萃分析。
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